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10.1002/cmdc.200700127

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C7162372!7162372 !17806092
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suck abstract from ncbi


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pmid17806092
      ChemMedChem 2008 ; 3 (3 ): 383-91
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  • Ferrocene conjugates of chloroquine and other antimalarials: the development of ferroquine, a new antimalarial #MMPMID17806092
  • Dive D ; Biot C
  • ChemMedChem 2008[Mar]; 3 (3 ): 383-91 PMID17806092 show ga
  • A convenient approach to antimalarial drug discovery is the use of the organic scaffold of a known antimalarial drug and an organometallic moiety to alter its unwanted properties and/or to optimize its initial effects. This minireview focuses mainly on the discovery of ferroquine, which has emerged from a collaborative French discovery project, and efforts to understand its mechanism of action and resistance.[Image: see text]
  • |Aminoquinolines/*pharmacology [MESH]
  • |Animals [MESH]
  • |Antimalarials/*pharmacology [MESH]
  • |Chloroquine/*pharmacology [MESH]
  • |Clinical Trials, Phase I as Topic [MESH]
  • |Drug Resistance [MESH]
  • |Ferrous Compounds/*pharmacology [MESH]
  • |Metallocenes [MESH]
  • |Organometallic Compounds/*pharmacology [MESH]


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