Drugs During Pregnancy and Lactation
2015[]; ? (?): 115-76
PMIDC7150338
show ga
Infections may be hazardous to the health of the mother, the course of pregnancy,
and the unborn child. They can lead to premature labor or premature rupture of
membranes and thereby increase the risk for spontaneous abortion and prematurity.
Furthermore, certain germs can pass to the unborn child and harm it directly.
Therefore, an anti-infective treatment which should be both effective and safe
for the mother and the unborn child is often required. The use of penicillines
and older cephalosporines is well documented and considered to be safe.
Consequently, they are the drug of choice during pregnancy. In selected cases of
bacterial resistance or intolerance to first-line antibiotics, other
anti-infective agents might be recommended. Especially for life-threatening
infections, a therapy with not so well-tried agents might be needed. The
potential benefit of treatment in such cases most often outbalances the potential
risk for the unborn child.
free
free
free
