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10.1007/s12325-020-01269-2 http://scihub22266oqcxt.onion/10.1007/s12325-020-01269-2 C7140756!7140756!32141017     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Adv+Ther 2020 ; 37 (4): 1360-80 Nephropedia Template TP {{tp|p=32141017|t=2020. Perioperative Antibiotics in Clean-Contaminated Head and Neck Surgery: A Systematic Review and Meta-Analysis |pdf=|usr=}}{{32141017}} gab.com Text Perioperative Antibiotics in Clean-Contaminated Head and Neck Surgery: A Systematic Review and Meta-Analysis JO: Adv Ther http://www.kidney.de/pget.php?&tw=1&pmid=32141017 #FOAvip Background: The optimal evidence-based prophylactic antibiotic regimen for surgical site infections following major head and neck surgery remains a matter of debate. Methods: Medline, Cochrane, and Embase were searched for the current best evidence. Retrieved manuscripts were screened according to the PRISMA guidelines. Included studies dealt with patients over 18 years of age that underwent clean-contaminated head and neck surgery (P) and compared the effect of an intervention, perioperative administration of different antibiotic regimens for a variable duration (I), with control groups receiving placebo, another antibiotic regimen, or the same antibiotic for a different postoperative duration (C), on surgical site infection rate as primary outcome (O) (PICO model). A systematic review was performed, and a selected group of trials investigating a similar research question was subjected to a random-effects model meta-analysis. Results: Thirty-nine studies were included in the systematic review. Compared with placebo, cefazolin, ampicillin?sulbactam, and amoxicillin?clavulanate were the most efficient agents. Benzylpenicillin and clindamycin were clearly less effective. Fifteen studies compared short- to long-term prophylaxis; treatment for more than 48 h did not further reduce wound infections. Meta-analysis of five clinical trials including 4336 patients, where clindamycin was compared with ampicillin?sulbactam, implied an increased infection rate for clindamycin-treated patients (OR?=?2.73, 95% CI 1.50?4.97, p?=?0.001). Conclusion: In clean-contaminated head and neck surgery, cefazolin, amoxicillin?clavulanate, and ampicillin?sulbactam for 24?48 h after surgery were associated with the highest prevention rate of surgical site infection. Twit Text FOAVip Perioperative Antibiotics in Clean-Contaminated Head and Neck Surgery: A Systematic Review and Meta-Analysis ????Adv Ther http://www.kidney.de/pget.php?&tw=1&pmid=32141017 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32141017 #FOAvip English Wikipedia <ref>{{Cite pmid|32141017}}</ref> Perioperative Antibiotics in Clean-Contaminated Head and Neck Surgery: A Systematic Review and Meta-Analysis #MMPMID32141017 Vander Poorten V; Uyttebroek S; Robbins KT; Rodrigo JP; de Bree R; Laenen A; F. Saba N; Suarez C; Mäkitie A; Rinaldo A; Ferlito A Adv Ther 2020[]; 37 (4): 1360-80 PMID32141017show ga Background: The optimal evidence-based prophylactic antibiotic regimen for surgical site infections following major head and neck surgery remains a matter of debate. Methods: Medline, Cochrane, and Embase were searched for the current best evidence. Retrieved manuscripts were screened according to the PRISMA guidelines. Included studies dealt with patients over 18 years of age that underwent clean-contaminated head and neck surgery (P) and compared the effect of an intervention, perioperative administration of different antibiotic regimens for a variable duration (I), with control groups receiving placebo, another antibiotic regimen, or the same antibiotic for a different postoperative duration (C), on surgical site infection rate as primary outcome (O) (PICO model). A systematic review was performed, and a selected group of trials investigating a similar research question was subjected to a random-effects model meta-analysis. Results: Thirty-nine studies were included in the systematic review. Compared with placebo, cefazolin, ampicillin?sulbactam, and amoxicillin?clavulanate were the most efficient agents. Benzylpenicillin and clindamycin were clearly less effective. Fifteen studies compared short- to long-term prophylaxis; treatment for more than 48 h did not further reduce wound infections. Meta-analysis of five clinical trials including 4336 patients, where clindamycin was compared with ampicillin?sulbactam, implied an increased infection rate for clindamycin-treated patients (OR?=?2.73, 95% CI 1.50?4.97, p?=?0.001). Conclusion: In clean-contaminated head and neck surgery, cefazolin, amoxicillin?clavulanate, and ampicillin?sulbactam for 24?48 h after surgery were associated with the highest prevention rate of surgical site infection. äPerioperative Antibiotics in Clean-Contaminated Head and Neck Surgery:(epmc).pdf DeepDyve Pubget Overpricing