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2020 ; 31
(2
): 128-136
Nephropedia Template TP
gab.com Text
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English Wikipedia
Emergence of deadly severe acute respiratory syndrome coronavirus-2 during
2019-2020
#MMPMID32292802
Islam A
; Ahmed A
; Naqvi IH
; Parveen S
Virusdisease
2020[Jun]; 31
(2
): 128-136
PMID32292802
show ga
Wuhan, the city in Hubei province in China is in the focus of global community
due to the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), formerly known as 2019-nCoV. The
virus emerged in humans from Wuhan seafood market probably via zoonotic
transmission. Within a few days the virus spread its tentacles rapidly to
neighboring cities in China and to different geographical regions through
travelers and to some extent by human to human transmission leading to
significant disease burden globally. More than 2,00,000 people (including more
than 8000 deaths) have been infected with this respiratory illness across 167
countries and territories worldwide leading to a pandemic. The present review
provides an outline about emergence and spread of SARS-CoV-2 from Wuhan, China in
2019-2020. We have also provided information about the classification, genome,
proteins, clinical presentation of COVID-19, type of clinical specimens to be
collected and diagnostic methods adopted to identify the respiratory illness. In
addition we have also provided information about transmission dynamics,
prevention measures and treatment options that are available at the present.
Subsequently, we have given a comprehensive overview of the spread of this
infection from China to the other parts of the globe. Management of the ongoing
outbreak of SARS-CoV-2 encompassing surveillance, clinical, immunological,
genetic and evolutionary investigations are likely to provide the desired
results. Joint efforts of global scientific community are needed at this hour in
terms of enhancement of research on development of accurate diagnostics,
antiviral therapeutics and finally into formation of an effective vaccine against
the emerging novel coronavirus.