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10.1016/j.jogoh.2020.101729

http://scihub22266oqcxt.onion/10.1016/j.jogoh.2020.101729
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suck abstract from ncbi


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pmid32247066
      J+Gynecol+Obstet+Hum+Reprod 2020 ; 49 (6 ): 101729
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  • Recommendations for the surgical management of gynecological cancers during the COVID-19 pandemic - FRANCOGYN group for the CNGOF #MMPMID32247066
  • Akladios C ; Azais H ; Ballester M ; Bendifallah S ; Bolze PA ; Bourdel N ; Bricou A ; Canlorbe G ; Carcopino X ; Chauvet P ; Collinet P ; Coutant C ; Dabi Y ; Dion L ; Gauthier T ; Graesslin O ; Huchon C ; Koskas M ; Kridelka F ; Lavoue V ; Lecointre L ; Mezzadri M ; Mimoun C ; Ouldamer L ; Raimond E ; Touboul C
  • J Gynecol Obstet Hum Reprod 2020[Jun]; 49 (6 ): 101729 PMID32247066 show ga
  • INTRODUCTION: In the context of the COVID-19 pandemic, specific recommendations are required for the management of patients with gynecologic cancer. MATERIALS AND METHOD: The FRANCOGYN group of the National College of French Gynecologists and Obstetricians (CNGOF) convened to develop recommendations based on the consensus conference model. RESULTS: If a patient with a gynecologic cancer presents with COVID-19, surgical management should be postponed for at least 15 days. For cervical cancer, radiotherapy and concomitant radiochemotherapy could replace surgery as first-line treatment and the value of lymph node staging should be reviewed on a case-by-case basis. For advanced ovarian cancers, neoadjuvant chemotherapy should be preferred over primary cytoreduction surgery. It is legitimate not to perform hyperthermic intraperitoneal chemotherapy during the COVID-19 pandemic. For patients who are scheduled to undergo interval surgery, chemotherapy can be continued and surgery performed after 6 cycles. For patients with early stage endometrial cancer of low and intermediate preoperative ESMO risk, hysterectomy with bilateral adnexectomy combined with a sentinel lymph node procedure is recommended. Surgery can be postponed for 1-2 months in low-risk endometrial cancers (FIGO Ia stage on MRI and grade 1-2 endometrioid cancer on endometrial biopsy). For patients of high ESMO risk, the MSKCC algorithm (combining PET-CT and sentinel lymph node biopsy) should be applied to avoid pelvic and lumbar-aortic lymphadenectomy. CONCLUSION: During the COVID-19 pandemic, management of a patient with cancer should be adapted to limit the risks associated with the virus without incurring loss of chance.
  • |*Betacoronavirus [MESH]
  • |*Pandemics/prevention & control [MESH]
  • |COVID-19 [MESH]
  • |Chemotherapy, Adjuvant [MESH]
  • |Coronavirus Infections/complications/*epidemiology/prevention & control [MESH]
  • |Endometrial Neoplasms/pathology/surgery [MESH]
  • |Female [MESH]
  • |France [MESH]
  • |Genital Neoplasms, Female/complications/pathology/*surgery/therapy [MESH]
  • |Gynecology [MESH]
  • |Humans [MESH]
  • |Interdisciplinary Communication [MESH]
  • |Obstetrics [MESH]
  • |Ovarian Neoplasms/drug therapy/pathology [MESH]
  • |Pneumonia, Viral/complications/*epidemiology/prevention & control [MESH]
  • |Receptors, Lymphocyte Homing [MESH]
  • |Risk [MESH]
  • |SARS-CoV-2 [MESH]
  • |Societies, Medical [MESH]
  • |Trophoblastic Neoplasms/drug therapy [MESH]
  • |Uterine Cervical Neoplasms/therapy [MESH]
  • |Vaginal Neoplasms/therapy [MESH]


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