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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Heart+Lung+Transplant
2020 ; 39
(5
): 412-417
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Epidemiologic and clinical characteristics of heart transplant recipients during
the 2019 coronavirus outbreak in Wuhan, China: A descriptive survey report
#MMPMID32362392
Ren ZL
; Hu R
; Wang ZW
; Zhang M
; Ruan YL
; Wu ZY
; Wu HB
; Hu XP
; Hu ZP
; Ren W
; Li LC
; Dai FF
; Liu H
; Cai X
J Heart Lung Transplant
2020[May]; 39
(5
): 412-417
PMID32362392
show ga
BACKGROUND: The epidemiologic and clinical characteristics of heart transplant
(HTx) recipients during the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) epidemic remains unclear. We studied the characteristics of HTx
recipients from December 20, 2019, to February 25, 2020, in an effort to
understand their risk and outcomes. METHODS: All accessible HTx recipients were
included in this single-center retrospective study. We collected information on
the recipients using a web-based questionnaire as well as the hospital database.
RESULTS: We followed 87 HTx recipients (72.4% were men, and the average age was
51 years). A total of 79 recipients resided in Hubei, and 57 recipients had a
Wuhan-related history of travel or contact. Most took precautionary measures
while in contact with suspicious crowds, and 96.6% of the families and
communities undertook prevention and quarantine procedures. Four upper airway
infections were reported, and 3 of them tested negative for SARS-CoV-2 (the
fourth recovered and was not tested). All cases were mild and successfully
recovered after proper treatment. Laboratory results of 47 HTx cases within the
last 2 months were extracted. Of these, 21.3% of recipients had pre-existing
lymphopenia, and 87.2% of recipients had a therapeutic concentration of
tacrolimus (5-12 ng/ml). Liver and kidney insufficiency was seen in 5 and 6
recipients, respectively. CONCLUSION: HTx recipients who practiced appropriate
prevention measures had a low rate of infection with SARS-CoV-2 and transition to
the associated disease COVID-19. These early data will require confirmation as
the pandemic establishes around the world.