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10.1155/2019/4124865 http://scihub22266oqcxt.onion/10.1155/2019/4124865 C6637675!6637675!31354812     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Interdiscip+Perspect+Infect+Dis 2019 ; 2019 (ä): ä Nephropedia Template TP {{tp|p=31354812|t=2019. Pathology of A(H5N8) (Clade 2 3 4 4) Virus in Experimentally Infected Chickens and Mice |pdf=|usr=}}{{31354812}} gab.com Text Pathology of A(H5N8) (Clade 2 3 4 4) Virus in Experimentally Infected Chickens and Mice JO: Interdiscip Perspect Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=31354812 #FOAvip The emergence of novel highly pathogenic avian influenza viruses (HPAIVs) in migratory birds raises serious concerns as these viruses have the potential to spread during fall migration. We report the identification of novel HPAIV A(H5N8) clade 2.3.4.4 virus that was isolated from sick domestic duck at commercial farm during the second wave of spread that began in October and affected poultry (ducks; chi?kens) in several European regions of Russia and Western Siberia in 2016. The strain was highly lethal in experimental infection of chickens and mice with IVPI = 2.34 and MLD50 = 1.3log10??EID50, accordingly. Inoculation of chickens with the HPAIV A/H5N8 demonstrated neuroinvasiveness, multiorgan failure, and death of chickens on the 3rd day post inoculation. Virus replicated in all collected organ samples in high viral titers with the highest titer in the brain (6.75±0.1 log10TCID50/ml). Effective virus replication was found in the following cells: neurons and glial cells of a brain; alveolar cells and macrophages of lungs; epithelial cells of a small intestine; hepatocytes and Kupffer cells of a liver; macrophages and endothelial cells of a spleen; and the tubular epithelial cells of kidneys. These findings advance our understanding of histopathological effect of A(H5N8) HPAIV infection. Twit Text FOAVip Pathology of A(H5N8) (Clade 2 3 4 4) Virus in Experimentally Infected Chickens and Mice ????Interdiscip Perspect Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=31354812 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31354812 #FOAvip English Wikipedia <ref>{{Cite pmid|31354812}}</ref> Pathology of A(H5N8) (Clade 2 3 4 4) Virus in Experimentally Infected Chickens and Mice #MMPMID31354812 Prokopyeva EA; Zinserling VA; Bae YC; Kwon Y; Kurskaya OG; Sobolev IA; Kozhin PM; Komissarov A; Fadeev A; Petrov V; Shestopalov AM; Sharshov KA Interdiscip Perspect Infect Dis 2019[]; 2019 (ä): ä PMID31354812show ga The emergence of novel highly pathogenic avian influenza viruses (HPAIVs) in migratory birds raises serious concerns as these viruses have the potential to spread during fall migration. We report the identification of novel HPAIV A(H5N8) clade 2.3.4.4 virus that was isolated from sick domestic duck at commercial farm during the second wave of spread that began in October and affected poultry (ducks; chi?kens) in several European regions of Russia and Western Siberia in 2016. The strain was highly lethal in experimental infection of chickens and mice with IVPI = 2.34 and MLD50 = 1.3log10??EID50, accordingly. Inoculation of chickens with the HPAIV A/H5N8 demonstrated neuroinvasiveness, multiorgan failure, and death of chickens on the 3rd day post inoculation. Virus replicated in all collected organ samples in high viral titers with the highest titer in the brain (6.75±0.1 log10TCID50/ml). Effective virus replication was found in the following cells: neurons and glial cells of a brain; alveolar cells and macrophages of lungs; epithelial cells of a small intestine; hepatocytes and Kupffer cells of a liver; macrophages and endothelial cells of a spleen; and the tubular epithelial cells of kidneys. These findings advance our understanding of histopathological effect of A(H5N8) HPAIV infection. äPathology of A(H5N8) (Clade 2 3 4 4) Virus in Experimentally Infected (epmc).pdf DeepDyve Pubget Overpricing