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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Influenza+Other+Respir+Viruses
2019 ; 13
(4
): 398-406
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Risk factors for seasonal influenza virus detection in stools of patients
consulting in general practice for acute respiratory infections in France,
2014-2016
#MMPMID29144593
Minodier L
; Masse S
; Capai L
; Blanchon T
; Ceccaldi PE
; van der Werf S
; Hanslik T
; Charrel R
; Falchi A
Influenza Other Respir Viruses
2019[Jul]; 13
(4
): 398-406
PMID29144593
show ga
BACKGROUND: Previous studies reported detection of influenza RNA in stools of
patients with seasonal influenza infection. While this detection may have a
clinical significance, other factors may influence the stool positivity for
influenza viruses. OBJECTIVES: The objective of this study was to investigate
demographical, clinical, and microbiological factors which could favor the
presence of influenza viral RNA in the stools of patients with
laboratory-confirmed influenza infection. METHODS: Acute respiratory infection
(ARI) patients were enrolled by general practitioners (GP) during two winter
seasons (2014-2016). Nasopharyngeal swabs, stool specimens, and clinical data
were collected. Samples were tested for 12 respiratory pathogen groups
(nasopharyngeal and stool specimens) and for 12 enteric pathogens (stool
specimens). RESULTS: Among the 331 patients with ARI enrolled by GP, 114 (34.4%)
presented influenza infection. Influenza RNA was detected in stool samples of 21%
(24/114) of the 114 stool specimens analyzed. Hospitalization (adjusted odds
ratio (aOR) = 7.8 (95% confidence interval (CI)) [1.7-33.7], P = .02), age
between 45 and 64 years (aOR = 4.8 [1.7-14.5], P = .01), consumption of raw
shellfish and/or mollusks (aOR = 16.7 [3.6-90.9], P = .00), and use of
antibiotics (aOR = 6.4 [2.1-19.8], P = .006) or antiviral treatment (aOR = 7.4
[1.9-29], P = .01) were significantly associated with an increased odds of the
detection of influenza RNA in stools. Among the 24 stool samples subjected to
viral isolation, no one showed virus growth. CONCLUSIONS: These findings will be
useful to studies investigating the dissemination route of influenza viruses to
gastrointestinal tract.