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10.24911/SJP.106-1516889879 http://scihub22266oqcxt.onion/10.24911/SJP.106-1516889879 C6378568!6378568!30799898     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sudan+J+Paediatr 2018 ; 18 (2): 42-7 Nephropedia Template TP {{tp|p=30799898|t=2018. Three cases of transient neonatal pseudohypoparathyroidism* |pdf=|usr=}}{{30799898}} gab.com Text Three cases of transient neonatal pseudohypoparathyroidism* JO: Sudan J Paediatr http://www.kidney.de/pget.php?&tw=1&pmid=30799898 #FOAvip Neonatal hypocalcemia is defined as serum calcium (S-Ca) < 2.0 mmol/l in full-term newborns and <1.75 mmol/l in preterm newborns. Neonatal hypocalcemia is either early onset (<3 days of age) or late onset (>3 days of age). Newborns with hypocalcemia are often asymptomatic but may present with hypotonia, apnea, poor feeding, jitteriness, seizures, and cardiac failure. Signs of hypocalcemia rarely occur unless S-Ca drops below 1.75 mmol/l. Neonatal hypocalcemia can be a result of hypoparathyroidism (transient or primary), increased serum calcitonin, sepsis, asphyxia, hepatopathy, hypomagnesemia, high phosphate load, transient hypoparathyroidism, and, rarely, transient neonatal pseudohypoparathyroidism [transient resistance to biological actions of parathyroid hormone (PTH)]. We present the case of three boys (two with gestational age 39 weeks, one 36 weeks; none of them with either asphyxia or sepsis) with mild hypotonia, where S-Ca in the range of 1.67?1.9 mmol/l was detected within the first 3 days of life, together with hyperphosphatemia [serum phosphate (P) 2.5?2.6 mmol/l], normomagnesemia [serum magnesium (S-Mg) 0.77?0.88 mmol/l], normal alkaline phosphatase (ALP) activity (2.8?4.5 ?kat/l), and high serum PTH (40?51 pg/ml; normal = 5?28). In spite of the gradual increase of S-Ca, the elevated serum PTH persisted beyond days 3, 4, and 6 in all three boys, together with normal or low-to-normal S-Ca, high or normal-to-high serum P, and no increases in serum ALP. The mothers S-Ca, P, Mg, ALP, and PTH levels were within normal reference ranges. With regard to laboratory results, the diagnosis of transient neonatal pseudohypoparathyroidism (due to immaturity of PTH-receptors) is highly probable in these three neonates. Twit Text FOAVip Three cases of transient neonatal pseudohypoparathyroidism* ????Sudan J Paediatr http://www.kidney.de/pget.php?&tw=1&pmid=30799898 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30799898 #FOAvip English Wikipedia <ref>{{Cite pmid|30799898}}</ref> Three cases of transient neonatal pseudohypoparathyroidism* #MMPMID30799898 Kutilek S; Vracovska M; Pecenkova K; Brozikova H; Rondzikova E; Boskova E; Pikner R; Fejfarkova Z Sudan J Paediatr 2018[]; 18 (2): 42-7 PMID30799898show ga Neonatal hypocalcemia is defined as serum calcium (S-Ca) < 2.0 mmol/l in full-term newborns and <1.75 mmol/l in preterm newborns. Neonatal hypocalcemia is either early onset (<3 days of age) or late onset (>3 days of age). Newborns with hypocalcemia are often asymptomatic but may present with hypotonia, apnea, poor feeding, jitteriness, seizures, and cardiac failure. Signs of hypocalcemia rarely occur unless S-Ca drops below 1.75 mmol/l. Neonatal hypocalcemia can be a result of hypoparathyroidism (transient or primary), increased serum calcitonin, sepsis, asphyxia, hepatopathy, hypomagnesemia, high phosphate load, transient hypoparathyroidism, and, rarely, transient neonatal pseudohypoparathyroidism [transient resistance to biological actions of parathyroid hormone (PTH)]. We present the case of three boys (two with gestational age 39 weeks, one 36 weeks; none of them with either asphyxia or sepsis) with mild hypotonia, where S-Ca in the range of 1.67?1.9 mmol/l was detected within the first 3 days of life, together with hyperphosphatemia [serum phosphate (P) 2.5?2.6 mmol/l], normomagnesemia [serum magnesium (S-Mg) 0.77?0.88 mmol/l], normal alkaline phosphatase (ALP) activity (2.8?4.5 ?kat/l), and high serum PTH (40?51 pg/ml; normal = 5?28). In spite of the gradual increase of S-Ca, the elevated serum PTH persisted beyond days 3, 4, and 6 in all three boys, together with normal or low-to-normal S-Ca, high or normal-to-high serum P, and no increases in serum ALP. The mothers S-Ca, P, Mg, ALP, and PTH levels were within normal reference ranges. With regard to laboratory results, the diagnosis of transient neonatal pseudohypoparathyroidism (due to immaturity of PTH-receptors) is highly probable in these three neonates. äThree cases of transient neonatal pseudohypoparathyroidism* (epmc).pdf DeepDyve Pubget Overpricing