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10.1128/JVI.01646-18 http://scihub22266oqcxt.onion/10.1128/JVI.01646-18 C6321928!6321928!30381485     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Virol 2019 ; 93 (2): ä Nephropedia Template TP {{tp|p=30381485|t=2019. Absence of ?6 Integrin Reduces Influenza Disease Severity in Highly Susceptible Obese Mice |pdf=|usr=}}{{30381485}} gab.com Text Absence of 6 Integrin Reduces Influenza Disease Severity in Highly Susceptible Obese Mice JO: J Virol http://www.kidney.de/pget.php?&tw=1&pmid=30381485 #FOAvip Obesity is a risk factor for developing severe influenza virus infection. However, the reasons for this are unknown. We found that the lungs of obese mice have increased expression of the epithelial integrin ?6, a host factor associated with increased disease severity. Knocking out integrin ?6 in obese mice favorably altered the pulmonary environment by increasing type I IFN signaling, resulting in decreased viral spread, reduced lung injury, and increased survival. This study furthers our understanding of influenza virus pathogenesis in the high-risk obese population and may potentially lead to the development of novel therapies for influenza virus infection. Twit Text FOAVip Absence of 6 Integrin Reduces Influenza Disease Severity in Highly Susceptible Obese Mice ????J Virol http://www.kidney.de/pget.php?&tw=1&pmid=30381485 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30381485 #FOAvip English Wikipedia <ref>{{Cite pmid|30381485}}</ref> Absence of ?6 Integrin Reduces Influenza Disease Severity in Highly Susceptible Obese Mice #MMPMID30381485 Meliopoulos V; Livingston B; Van de Velde LA; Honce R; Schultz-Cherry S J Virol 2019[Jan]; 93 (2): ä PMID30381485show ga Obesity is a risk factor for developing severe influenza virus infection. However, the reasons for this are unknown. We found that the lungs of obese mice have increased expression of the epithelial integrin ?6, a host factor associated with increased disease severity. Knocking out integrin ?6 in obese mice favorably altered the pulmonary environment by increasing type I IFN signaling, resulting in decreased viral spread, reduced lung injury, and increased survival. This study furthers our understanding of influenza virus pathogenesis in the high-risk obese population and may potentially lead to the development of novel therapies for influenza virus infection. äAbsence of ?6 Integrin Reduces Influenza Disease Severity in Highly Su(epmc).pdf DeepDyve Pubget Overpricing