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2018 ; 10
(11
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Additional Vitamin and Mineral Support for Patients with Severe Burns: A
Nationwide Experience from a Catastrophic Color-Dust Explosion Event in Taiwan
#MMPMID30453517
Chen LR
; Yang BS
; Chang CN
; Yu CM
; Chen KH
Nutrients
2018[Nov]; 10
(11
): ä PMID30453517
show ga
Major burn injuries, which encompass ?20% of the total body surface area (TBSA),
are the most severe form of trauma because of the stress response they provoke,
which includes hypermetabolism, muscle wasting, and stress-induced diabetes. In
2015, a color-dust explosion disaster occurred in the Formosa Fun Coast of Taiwan
and injured 499 people, who were transferred via a nationwide emergency delivery
system. Some recommendations are currently available regarding vitamin and
mineral support for wound healing and recovery in severe burns, but there is a
lack of evidence to confirm the benefits. Thus, the current study aimed to
investigate the effects of additional vitamin and mineral support for patients
with severe burn injuries. Sixty-one hospitalized individuals with major burns
(full thickness and ?20% TBSA) were classified into the supplement (n = 30) and
control (n = 31) groups, according to whether they received supplementation with
additional vitamins, calcium, and magnesium. There were significant differences
between the supplement and control groups in the incidence of wound infection
(30.0% vs. 77.4%, p < 0.001), sepsis (13.3% vs. 41.9%, p = 0.021), and
hospitalization days (51.80 vs. 76.81, p = 0.025). After adjustment, logistic
regression analysis revealed that, compared to those in the control group,
patients in the supplement group had a lower risk for wound infection (OR 0.11;
95% CI 0.03?0.43; p = 0.002) and sepsis (OR 0.09; 95% CI 0.01?0.61; p = 0.014).
Supplementation of multiple vitamins, calcium, and magnesium reduced the risk of
wound infection and sepsis, shortened the time of hospitalization, and can be
considered for use in major burns.
|*Dietary Supplements
[MESH]
|Adolescent
[MESH]
|Adult
[MESH]
|Blast Injuries/*epidemiology/prevention & control
[MESH]
|Body Mass Index
[MESH]
|Burns/*therapy
[MESH]
|Case-Control Studies
[MESH]
|Dust
[MESH]
|Explosions
[MESH]
|Female
[MESH]
|Humans
[MESH]
|Incidence
[MESH]
|Male
[MESH]
|Sepsis/*epidemiology/prevention & control
[MESH]
|Taiwan/epidemiology
[MESH]
|Trace Elements/*administration & dosage
[MESH]
|Vitamins/*administration & dosage
[MESH]
|Wound Healing
[MESH]
|Wound Infection/*epidemiology/prevention & control
[MESH]