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10.3960/jslrt.17006 http://scihub22266oqcxt.onion/10.3960/jslrt.17006 C6144272!6144272!28496056     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Exp+Hematop 2017 ; 57 (1): 21-5 Nephropedia Template TP {{tp|p=28496056|t=2017. Stat3 inhibitor abrogates the expression of PD-1 ligands on lymphoma cell lines |pdf=|usr=}}{{28496056}} gab.com Text Stat3 inhibitor abrogates the expression of PD-1 ligands on lymphoma cell lines JO: J Clin Exp Hematop http://www.kidney.de/pget.php?&tw=1&pmid=28496056 #FOAvip Recent studies have indicated the significance of immune checkpoint molecules including programmed death-1 (PD-1), cytotoxic T-lymphocyte associated protein 4, and T-cell immunoglobulin and mucin domain-containing molecule-3 for anti-tumor immune responses. We previously investigated PD-1 ligand 1/2 (PD-L1/2) expression in lymphoma cell lines, and found that PD-L1/2 is expressed on the adult T-cell leukemia/lymphoma (ATL-T) and B-cell lymphoma (SLVL) cell lines. In the present study, we investigated whether the Stat3 inhibitor WP1066 abrogated PD-L1/2 expression in lymphoma cell lines. Incubation with WP1066 inhibited lymphoma cell growth and induced cell apoptosis. PD-L1/2 expression in the ATL-T, SLVL, and human brain malignant lymphoma (HKBML) cell lines was significantly abrogated by WP1066 treatment. These data indicated that a Stat3 inhibitor abrogated PD-L1/2 expression in lymphoma cells. Such an inhibitor is therefore considered to be useful for additional immunotherapy in patients with advanced lymphoma. Twit Text FOAVip Stat3 inhibitor abrogates the expression of PD-1 ligands on lymphoma cell lines ????J Clin Exp Hematop http://www.kidney.de/pget.php?&tw=1&pmid=28496056 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28496056 #FOAvip English Wikipedia <ref>{{Cite pmid|28496056}}</ref> Stat3 inhibitor abrogates the expression of PD-1 ligands on lymphoma cell lines #MMPMID28496056 Ma C; Horlad H; Pan C; Yano H; Ohnishi K; Fujiwara Y; Matsuoka M; Lee A; Niidome T; Yamanaka R; Takeya M; Komohara Y J Clin Exp Hematop 2017[Jul]; 57 (1): 21-5 PMID28496056show ga Recent studies have indicated the significance of immune checkpoint molecules including programmed death-1 (PD-1), cytotoxic T-lymphocyte associated protein 4, and T-cell immunoglobulin and mucin domain-containing molecule-3 for anti-tumor immune responses. We previously investigated PD-1 ligand 1/2 (PD-L1/2) expression in lymphoma cell lines, and found that PD-L1/2 is expressed on the adult T-cell leukemia/lymphoma (ATL-T) and B-cell lymphoma (SLVL) cell lines. In the present study, we investigated whether the Stat3 inhibitor WP1066 abrogated PD-L1/2 expression in lymphoma cell lines. Incubation with WP1066 inhibited lymphoma cell growth and induced cell apoptosis. PD-L1/2 expression in the ATL-T, SLVL, and human brain malignant lymphoma (HKBML) cell lines was significantly abrogated by WP1066 treatment. These data indicated that a Stat3 inhibitor abrogated PD-L1/2 expression in lymphoma cells. Such an inhibitor is therefore considered to be useful for additional immunotherapy in patients with advanced lymphoma. äStat3 inhibitor abrogates the expression of PD-1 ligands on lymphoma c(epmc).pdf DeepDyve Pubget Overpricing