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10.1038/s41467-018-05376-1 http://scihub22266oqcxt.onion/10.1038/s41467-018-05376-1 C6063940!6063940!30054479     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2018 ; 9 (ä): ä Nephropedia Template TP {{tp|p=30054479|t=2018. Scutoids are a geometrical solution to three-dimensional packing of epithelia |pdf=|usr=}}{{30054479}} gab.com Text Scutoids are a geometrical solution to three-dimensional packing of epithelia JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=30054479 #FOAvip As animals develop, tissue bending contributes to shape the organs into complex three-dimensional structures. However, the architecture and packing of curved epithelia remains largely unknown. Here we show by means of mathematical modelling that cells in bent epithelia can undergo intercalations along the apico-basal axis. This phenomenon forces cells to have different neighbours in their basal and apical surfaces. As a consequence, epithelial cells adopt a novel shape that we term ?scutoid?. The detailed analysis of diverse tissues confirms that generation of apico-basal intercalations between cells is a common feature during morphogenesis. Using biophysical arguments, we propose that scutoids make possible the minimization of the tissue energy and stabilize three-dimensional packing. Hence, we conclude that scutoids are one of nature's solutions to achieve epithelial bending. Our findings pave the way to understand the three-dimensional organization of epithelial organs. Twit Text FOAVip Scutoids are a geometrical solution to three-dimensional packing of epithelia ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=30054479 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30054479 #FOAvip English Wikipedia <ref>{{Cite pmid|30054479}}</ref> Scutoids are a geometrical solution to three-dimensional packing of epithelia #MMPMID30054479 Gómez-Gálvez P; Vicente-Munuera P; Tagua A; Forja C; Castro AM; Letrán M; Valencia-Expósito A; Grima C; Bermúdez-Gallardo M; Serrano-Pérez-Higueras Ó; Cavodeassi F; Sotillos S; Martín-Bermudo MD; Márquez A; Buceta J; Escudero LM Nat Commun 2018[]; 9 (ä): ä PMID30054479show ga As animals develop, tissue bending contributes to shape the organs into complex three-dimensional structures. However, the architecture and packing of curved epithelia remains largely unknown. Here we show by means of mathematical modelling that cells in bent epithelia can undergo intercalations along the apico-basal axis. This phenomenon forces cells to have different neighbours in their basal and apical surfaces. As a consequence, epithelial cells adopt a novel shape that we term ?scutoid?. The detailed analysis of diverse tissues confirms that generation of apico-basal intercalations between cells is a common feature during morphogenesis. Using biophysical arguments, we propose that scutoids make possible the minimization of the tissue energy and stabilize three-dimensional packing. Hence, we conclude that scutoids are one of nature's solutions to achieve epithelial bending. Our findings pave the way to understand the three-dimensional organization of epithelial organs. äScutoids are a geometrical solution to three-dimensional packing of ep(epmc).pdf DeepDyve Pubget Overpricing