Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1038/s41598-018-28749-4 http://scihub22266oqcxt.onion/10.1038/s41598-018-28749-4 C6062510!6062510!30050104     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2018 ; 8 (ä): ä Nephropedia Template TP {{tp|p=30050104|t=2018. The habu genome reveals accelerated evolution of venom protein genes |pdf=|usr=}}{{30050104}} gab.com Text The habu genome reveals accelerated evolution of venom protein genes JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=30050104 #FOAvip Evolution of novel traits is a challenging subject in biological research. Several snake lineages developed elaborate venom systems to deliver complex protein mixtures for prey capture. To understand mechanisms involved in snake venom evolution, we decoded here the ~1.4-Gb genome of a habu, Protobothrops flavoviridis. We identified 60 snake venom protein genes (SV) and 224 non-venom paralogs (NV), belonging to 18 gene families. Molecular phylogeny reveals early divergence of SV and NV genes, suggesting that one of the four copies generated through two rounds of whole-genome duplication was modified for use as a toxin. Among them, both SV and NV genes in four major components were extensively duplicated after their diversification, but accelerated evolution is evident exclusively in the SV genes. Both venom-related SV and NV genes are significantly enriched in microchromosomes. The present study thus provides a genetic background for evolution of snake venom composition. Twit Text FOAVip The habu genome reveals accelerated evolution of venom protein genes ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=30050104 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30050104 #FOAvip English Wikipedia <ref>{{Cite pmid|30050104}}</ref> The habu genome reveals accelerated evolution of venom protein genes #MMPMID30050104 Shibata H; Chijiwa T; Oda-Ueda N; Nakamura H; Yamaguchi K; Hattori S; Matsubara K; Matsuda Y; Yamashita A; Isomoto A; Mori K; Tashiro K; Kuhara S; Yamasaki S; Fujie M; Goto H; Koyanagi R; Takeuchi T; Fukumaki Y; Ohno M; Shoguchi E; Hisata K; Satoh N; Ogawa T Sci Rep 2018[]; 8 (ä): ä PMID30050104show ga Evolution of novel traits is a challenging subject in biological research. Several snake lineages developed elaborate venom systems to deliver complex protein mixtures for prey capture. To understand mechanisms involved in snake venom evolution, we decoded here the ~1.4-Gb genome of a habu, Protobothrops flavoviridis. We identified 60 snake venom protein genes (SV) and 224 non-venom paralogs (NV), belonging to 18 gene families. Molecular phylogeny reveals early divergence of SV and NV genes, suggesting that one of the four copies generated through two rounds of whole-genome duplication was modified for use as a toxin. Among them, both SV and NV genes in four major components were extensively duplicated after their diversification, but accelerated evolution is evident exclusively in the SV genes. Both venom-related SV and NV genes are significantly enriched in microchromosomes. The present study thus provides a genetic background for evolution of snake venom composition. äThe habu genome reveals accelerated evolution of venom protein genes (epmc).pdf DeepDyve Pubget Overpricing