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10.1186/s13054-018-2103-0

http://scihub22266oqcxt.onion/10.1186/s13054-018-2103-0
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C6060511!6060511!30045753
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suck abstract from ncbi


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pmid30045753      Crit+Care 2018 ; 22 (ä): ä
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  • Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome: a systematic review and meta-analysis #MMPMID30045753
  • Van Damme L; De Waele JJ
  • Crit Care 2018[]; 22 (ä): ä PMID30045753show ga
  • Background: Decompressive laparotomy has been advised as potential treatment for abdominal compartment syndrome (ACS) when medical management fails; yet, the effect on parameters of organ function differs markedly in the published literature. In this study, we sought to investigate the effect of decompressive laparotomy on intra-abdominal pressure and organ function in critically ill adult and pediatric patients with ACS, specifically focusing on hemodynamic, respiratory, and kidney function and outcome. Methods: A systematic review and meta-analysis of the literature was performed. Articles reporting data on intra-abdominal pressure (IAP), hemodynamic (mean arterial pressures [MAP], central venous pressure [CVP], cardiac index [CI], heart rate [HR], systemic vascular resistance index [SVRI] and/or pulmonary capillary wedge pressure [PCWP]), respiratory (positive end-expiratory pressure [PEEP], peak inspiratory pressure [PIP] and/or ratio of partial pressure arterial oxygen and fraction of inspired oxygen [P/F ratio]), and/or urinary output (UO) following decompressive laparotomy were analyzed. Results: A total of 15 articles were included; 3 included children only (aged 18 years or younger). Of the 286 patients who were included, 49.7% had primary ACS. The baseline mean IAP in adults decreased with an average of 18.2?±?6.5 mmHg following decompression, from 31.7?±?6.4 mmHg to 13.5?±?3.0 mmHg. There was a decrease in HR (12.2?±?9.5 beats/min; p?=?0.04), CVP (4.6?±?2.3 mmHg; p?=?0.022), PCWP (5.8?±?2.3 mmHg; p?=?0.029), and PIP (10.1?±?3.9 cmH2O; p?
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