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10.3389/fimmu.2018.01630 http://scihub22266oqcxt.onion/10.3389/fimmu.2018.01630 C6054970!6054970!30061896     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2018 ; 9 (ä): ä Nephropedia Template TP {{tp|p=30061896|t=2018. Potential Pathways Associated With Exaggerated T Follicular Helper Response in Human Autoimmune Diseases |pdf=|usr=}}{{30061896}} gab.com Text Potential Pathways Associated With Exaggerated T Follicular Helper Response in Human Autoimmune Diseases JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=30061896 #FOAvip Convincing lines of evidence in both mice and humans show that exaggerated T follicular helper (Tfh) responses is pathogenic in autoimmune diseases. However, the cause of exaggerated Tfh response in humans is still much less clear than in mouse models where genetic factors can be manipulated for in vivo testing. Nonetheless, recent advances in our understanding on the mechanisms of human Tfh differentiation and identification of multiple risk loci in genome-wide association studies have revealed several pathways potentially associated with exaggerated Tfh response in human autoimmune diseases. In this review, we will first briefly summarize the differentiation mechanisms of Tfh cells in humans. We describe the features of ?Tfh-like? cells recently identified in inflamed tissues of human autoimmune diseases. Then we will discuss how risk loci identified in GWAS are potentially involved in exaggerated Tfh response in human autoimmune diseases. Twit Text FOAVip Potential Pathways Associated With Exaggerated T Follicular Helper Response in Human Autoimmune Diseases ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=30061896 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30061896 #FOAvip English Wikipedia <ref>{{Cite pmid|30061896}}</ref> Potential Pathways Associated With Exaggerated T Follicular Helper Response in Human Autoimmune Diseases #MMPMID30061896 Horiuchi S; Ueno H Front Immunol 2018[]; 9 (ä): ä PMID30061896show ga Convincing lines of evidence in both mice and humans show that exaggerated T follicular helper (Tfh) responses is pathogenic in autoimmune diseases. However, the cause of exaggerated Tfh response in humans is still much less clear than in mouse models where genetic factors can be manipulated for in vivo testing. Nonetheless, recent advances in our understanding on the mechanisms of human Tfh differentiation and identification of multiple risk loci in genome-wide association studies have revealed several pathways potentially associated with exaggerated Tfh response in human autoimmune diseases. In this review, we will first briefly summarize the differentiation mechanisms of Tfh cells in humans. We describe the features of ?Tfh-like? cells recently identified in inflamed tissues of human autoimmune diseases. Then we will discuss how risk loci identified in GWAS are potentially involved in exaggerated Tfh response in human autoimmune diseases. äPotential Pathways Associated With Exaggerated T Follicular Helper Res(epmc).pdf DeepDyve Pubget Overpricing