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10.1001/jamaophthalmol.2016.4224

http://scihub22266oqcxt.onion/10.1001/jamaophthalmol.2016.4224
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suck abstract from ncbi


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pmid27832248
      JAMA+Ophthalmol 2016 ; 134 (12 ): 1402-1408
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  • Binocular iPad Game vs Patching for Treatment of Amblyopia in Children: A Randomized Clinical Trial #MMPMID27832248
  • Kelly KR ; Jost RM ; Dao L ; Beauchamp CL ; Leffler JN ; Birch EE
  • JAMA Ophthalmol 2016[Dec]; 134 (12 ): 1402-1408 PMID27832248 show ga
  • IMPORTANCE: Fellow eye patching has long been the standard treatment for amblyopia, but it does not always restore 20/20 vision or teach the eyes to work together. Amblyopia can be treated with binocular games that rebalance contrast between the eyes so that a child may overcome suppression. However, it is unclear whether binocular treatment is comparable to patching in treating amblyopia. OBJECTIVES: To assess the effectiveness of a binocular iPad (Apple Inc) adventure game as amblyopia treatment and compare this binocular treatment with patching, the current standard of care. DESIGN, SETTING, AND PARTICIPANTS: This investigation was a randomized clinical trial with a crossover design at a nonprofit eye research institute. Between February 20, 2015, and January 4, 2016, a total of 28 patients were enrolled in the study, with 14 randomized to binocular game treatment and 14 to patching treatment. INTERVENTIONS: Binocular game and patching as amblyopia treatments. MAIN OUTCOMES AND MEASURES: The primary outcome was change in amblyopic eye best-corrected visual acuity (BCVA) at the 2-week visit. Secondary outcomes were change in stereoacuity and suppression at the 2-week visit and change in BCVA at the 4-week visit. RESULTS: Among 28 children, the mean (SD) age at baseline was 6.7 (1.4) years (age range, 4.6-9.5 years), and 7 (25%) were female. At baseline, the mean (SD) amblyopic eye BCVA was 0.48 (0.14) logMAR (approximately 20/63; range, 0.3-0.8 logMAR [20/40 to 20/125]), with 14 children randomized to the binocular game and 14 to patching for 2 weeks. At the 2-week visit, improvement in amblyopic eye BCVA was greater with the binocular game compared with patching, with a mean (SD) improvement of 0.15 (0.08) logMAR (mean [SD], 1.5 [0.8] lines) vs 0.07 (0.08) logMAR (mean [SD], 0.7 [0.8] line; P?=?.02) after 2 weeks of treatment. These improvements from baseline were significant for the binocular game (mean [SD] improvement, 1.5 [0.8] lines; P?
  • |*Computers, Handheld [MESH]
  • |*Eyeglasses [MESH]
  • |*Video Games [MESH]
  • |Amblyopia/*physiopathology/therapy [MESH]
  • |Child [MESH]
  • |Child, Preschool [MESH]
  • |Cross-Over Studies [MESH]
  • |Female [MESH]
  • |Follow-Up Studies [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Retrospective Studies [MESH]
  • |Treatment Outcome [MESH]
  • |Vision, Binocular/*physiology [MESH]


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