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10.1097/MNH.0000000000000384 http://scihub22266oqcxt.onion/10.1097/MNH.0000000000000384 C6053669!6053669 !29135585     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29135585 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Nephrol+Hypertens 2018 ; 27 (2 ): 63-69 Nephropedia Template TP {{tp|p=29135585 |t=2018. The regulation of aldosterone secretion by leptin: implications in obesity-related cardiovascular disease |pdf=|usr=}}{{29135585 }} gab.com Text The regulation of aldosterone secretion by leptin: implications in obesity-related cardiovascular disease JO: Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=29135585 #FOAvip PURPOSE OF REVIEW: Although it has been known for some time that increases in body mass enhance aldosterone secretion, particularly in women, the origin of this elevation in aldosterone production is not well defined. Adipocyte-derived factors have emerged as potential candidates to increase aldosterone production in obesity. RECENT FINDINGS: Emerging evidence suggests the presence of a mechanistic link in which the adipocyte-derived hormone leptin stimulates aldosterone production in obesity, thereby creating a positive feedback loop for obesity-associated cardiovascular disease. In addition, recent reports give credence to the concept that this leptin-aldosterone stimulation pathway in obesity is an underlying mechanism for sex-discrepancies in obesity-associated cardiovascular disease. SUMMARY: Leptin appears as a new direct regulator of adrenal aldosterone production and leptin-mediated aldosterone production is a novel candidate mechanism underlying obesity-associated hypertension, particularly in females. Twit Text FOAVip The regulation of aldosterone secretion by leptin: implications in obesity-related cardiovascular disease ????Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=29135585 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29135585 #FOAvip English Wikipedia <ref>{{Cite pmid|29135585 }}</ref> The regulation of aldosterone secretion by leptin: implications in obesity-related cardiovascular disease #MMPMID29135585 Faulkner JL ; Bruder-Nascimento T ; Belin de Chantemèle EJ Curr Opin Nephrol Hypertens 2018[Mar]; 27 (2 ): 63-69 PMID29135585 show ga PURPOSE OF REVIEW: Although it has been known for some time that increases in body mass enhance aldosterone secretion, particularly in women, the origin of this elevation in aldosterone production is not well defined. Adipocyte-derived factors have emerged as potential candidates to increase aldosterone production in obesity. RECENT FINDINGS: Emerging evidence suggests the presence of a mechanistic link in which the adipocyte-derived hormone leptin stimulates aldosterone production in obesity, thereby creating a positive feedback loop for obesity-associated cardiovascular disease. In addition, recent reports give credence to the concept that this leptin-aldosterone stimulation pathway in obesity is an underlying mechanism for sex-discrepancies in obesity-associated cardiovascular disease. SUMMARY: Leptin appears as a new direct regulator of adrenal aldosterone production and leptin-mediated aldosterone production is a novel candidate mechanism underlying obesity-associated hypertension, particularly in females. |Adipocytes/*metabolism [MESH] |Aldosterone/*metabolism [MESH] |Animals [MESH] |Cardiovascular Diseases/etiology/*metabolism [MESH] |Humans [MESH] |Leptin/*metabolism [MESH] |Obesity/complications/*metabolism [MESH]The regulation of aldosterone secretion by leptin: implications in o(epmc).pdf DeepDyve Pubget Overpricing