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10.1016/j.bpj.2018.06.013 http://scihub22266oqcxt.onion/10.1016/j.bpj.2018.06.013 C6051480!6051480!30021115     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biophys+J 2018 ; 115 (2): 411-25 Nephropedia Template TP {{tp|p=30021115|t=2018. Antimargination of Microparticles and Platelets in the Vicinity of Branching Vessels |pdf=|usr=}}{{30021115}} gab.com Text Antimargination of Microparticles and Platelets in the Vicinity of Branching Vessels JO: Biophys J http://www.kidney.de/pget.php?&tw=1&pmid=30021115 #FOAvip We investigate the margination of microparticles/platelets in blood flow through complex geometries typical for in vivo vessel networks: a vessel confluence and a bifurcation. Using three-dimensional lattice Boltzmann simulations, we confirm that behind the confluence of two vessels, a cell-free layer devoid of red blood cells develops in the channel center. Despite its small size of roughly 1 ?m, this central cell-free layer persists for up to 100 ?m after the confluence. Most importantly, we show from simulations that this layer also contains a significant amount of microparticles/platelets and validate this result by in vivo microscopy in mouse venules. At bifurcations, however, a similar effect does not appear, and margination is largely unaffected by the geometry. This antimargination toward the vessel center after a confluence may explain earlier in vivo observations, which found that platelet concentrations near the vessel wall are seen to be much higher on the arteriolar side (containing bifurcations) than on the venular side (containing confluences) of the vascular system. Twit Text FOAVip Antimargination of Microparticles and Platelets in the Vicinity of Branching Vessels ????Biophys J http://www.kidney.de/pget.php?&tw=1&pmid=30021115 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30021115 #FOAvip English Wikipedia <ref>{{Cite pmid|30021115}}</ref> Antimargination of Microparticles and Platelets in the Vicinity of Branching Vessels #MMPMID30021115 Bächer C; Kihm A; Schrack L; Kaestner L; Laschke MW; Wagner C; Gekle S Biophys J 2018[Jul]; 115 (2): 411-25 PMID30021115show ga We investigate the margination of microparticles/platelets in blood flow through complex geometries typical for in vivo vessel networks: a vessel confluence and a bifurcation. Using three-dimensional lattice Boltzmann simulations, we confirm that behind the confluence of two vessels, a cell-free layer devoid of red blood cells develops in the channel center. Despite its small size of roughly 1 ?m, this central cell-free layer persists for up to 100 ?m after the confluence. Most importantly, we show from simulations that this layer also contains a significant amount of microparticles/platelets and validate this result by in vivo microscopy in mouse venules. At bifurcations, however, a similar effect does not appear, and margination is largely unaffected by the geometry. This antimargination toward the vessel center after a confluence may explain earlier in vivo observations, which found that platelet concentrations near the vessel wall are seen to be much higher on the arteriolar side (containing bifurcations) than on the venular side (containing confluences) of the vascular system. äAntimargination of Microparticles and Platelets in the Vicinity of Bra(epmc).pdf DeepDyve Pubget Overpricing