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10.1093/eep/dvy016 http://scihub22266oqcxt.onion/10.1093/eep/dvy016 C6051467!6051467!30038800     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Environ+Epigenet 2018 ; 4 (2): ä Nephropedia Template TP {{tp|p=30038800|t=2018. Environmentally induced epigenetic transgenerational inheritance of disease |pdf=|usr=}}{{30038800}} gab.com Text Environmentally induced epigenetic transgenerational inheritance of disease JO: Environ Epigenet http://www.kidney.de/pget.php?&tw=1&pmid=30038800 #FOAvip Ancestral environmental exposures such as toxicants, abnormal nutrition or stress can promote the epigenetic transgenerational inheritance of disease and phenotypic variation. These environmental factors induce the epigenetic reprogramming of the germline (sperm and egg). The germline epimutations can in turn increase disease susceptibility of subsequent generations of the exposed ancestors. A variety of environmental factors, species and exposure specificity of this induced epigenetic transgenerational inheritance of disease is discussed with a consideration of generational toxicology. The molecular mechanisms and processes involved in the ability of these inherited epimutations to increase disease susceptibility are discussed. In addition to altered disease susceptibility, the potential impact of the epigenetic inheritance on phenotypic variation and evolution is considered. Observations suggest environmentally induced epigenetic transgenerational inheritance of disease is a critical aspect of disease etiology, toxicology and evolution that needs to be considered. Twit Text FOAVip Environmentally induced epigenetic transgenerational inheritance of disease ????Environ Epigenet http://www.kidney.de/pget.php?&tw=1&pmid=30038800 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30038800 #FOAvip English Wikipedia <ref>{{Cite pmid|30038800}}</ref> Environmentally induced epigenetic transgenerational inheritance of disease #MMPMID30038800 Nilsson EE; Sadler-Riggleman I; Skinner MK Environ Epigenet 2018[Apr]; 4 (2): ä PMID30038800show ga Ancestral environmental exposures such as toxicants, abnormal nutrition or stress can promote the epigenetic transgenerational inheritance of disease and phenotypic variation. These environmental factors induce the epigenetic reprogramming of the germline (sperm and egg). The germline epimutations can in turn increase disease susceptibility of subsequent generations of the exposed ancestors. A variety of environmental factors, species and exposure specificity of this induced epigenetic transgenerational inheritance of disease is discussed with a consideration of generational toxicology. The molecular mechanisms and processes involved in the ability of these inherited epimutations to increase disease susceptibility are discussed. In addition to altered disease susceptibility, the potential impact of the epigenetic inheritance on phenotypic variation and evolution is considered. Observations suggest environmentally induced epigenetic transgenerational inheritance of disease is a critical aspect of disease etiology, toxicology and evolution that needs to be considered. äEnvironmentally induced epigenetic transgenerational inheritance of di(epmc).pdf DeepDyve Pubget Overpricing