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2018 ; 2018
(ä): 8092702
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Research Priorities and Resource Allocation in the Investigation of New Drugs for
Cancer in Least Developed Countries
#MMPMID30057606
da Silva RE
; Amato AA
; Andrade DDBC
; Leite E Silva AV
; de Carvalho MR
; Novaes MRCG
J Oncol
2018[]; 2018
(ä): 8092702
PMID30057606
show ga
Cancer incidence has increased significantly in low- and middle-income countries.
The priorities of international health research are not always aligned with the
global burden of cancer. This study aims to analyze global tendencies in clinical
trials in oncology and discuss research priorities and resource allocation in the
investigation of new drugs for cancers that significantly affect the least
developed countries. This was a retrospective and analytical study that included
data collected from the World Health Organization's International Clinical Trials
Registry Platform (ICTRP) in 2014. According to our results, there was a tendency
for clinical trials involving breast and lung cancer to be conducted in countries
with a lower level of economic development. On the other hand, cervical, stomach,
and liver cancer, despite the significant burden that these place on middle- and
low-income countries, were studied little among the countries selected. In
conclusion, the organizations that most fund research to develop new drugs for
cancer treatment continue to show little interest in prioritizing resources to
fund research for certain types of cancer such as those of the cervix, stomach,
and liver, which have a significant impact in low- and middle-income countries.
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