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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Mult+Scler+J+Exp+Transl+Clin
2018 ; 4
(3
): 2055217318788699
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High prevalence and indexes of anti-John Cunningham virus antibodies in a cohort
of Chinese patients with multiple sclerosis
#MMPMID30038791
Lau A
; Qiu W
; Kermode A
; Au C
; Ng A
; Wong A
; Ma SH
; Au L
; Ma K
; Ip B
; Mok V
Mult Scler J Exp Transl Clin
2018[Jul]; 4
(3
): 2055217318788699
PMID30038791
show ga
We performed a cross-sectional study in 123 Chinese multiple sclerosis patients
residing in Hong Kong to evaluate their anti-John Cunningham virus status using
STRATIFY JCV DxSelect assays. Anti-John Cunningham virus antibody was present in
98/123 (80%) subjects, among which 75/98 (77%) had an anti-John Cunningham virus
index ?1.5. Anti-John Cunningham virus antibody seropositivity was not correlated
with age, disease duration, Expanded Disability Status Scale scores, types of
multiple sclerosis (relapsing vs progressive), or disease-modifying treatments
used. We found a very high seroprevalence and index of anti-John Cunningham virus
antibodies in Chinese multiple sclerosis patients, which may impact the risk
assessment and recommendation of disease-modifying treatments in this population.