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10.1177/2055217318788699

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C6050819!6050819 !30038791
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suck abstract from ncbi


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pmid30038791
      Mult+Scler+J+Exp+Transl+Clin 2018 ; 4 (3 ): 2055217318788699
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  • High prevalence and indexes of anti-John Cunningham virus antibodies in a cohort of Chinese patients with multiple sclerosis #MMPMID30038791
  • Lau A ; Qiu W ; Kermode A ; Au C ; Ng A ; Wong A ; Ma SH ; Au L ; Ma K ; Ip B ; Mok V
  • Mult Scler J Exp Transl Clin 2018[Jul]; 4 (3 ): 2055217318788699 PMID30038791 show ga
  • We performed a cross-sectional study in 123 Chinese multiple sclerosis patients residing in Hong Kong to evaluate their anti-John Cunningham virus status using STRATIFY JCV DxSelect assays. Anti-John Cunningham virus antibody was present in 98/123 (80%) subjects, among which 75/98 (77%) had an anti-John Cunningham virus index ?1.5. Anti-John Cunningham virus antibody seropositivity was not correlated with age, disease duration, Expanded Disability Status Scale scores, types of multiple sclerosis (relapsing vs progressive), or disease-modifying treatments used. We found a very high seroprevalence and index of anti-John Cunningham virus antibodies in Chinese multiple sclerosis patients, which may impact the risk assessment and recommendation of disease-modifying treatments in this population.
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