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10.3389/fimmu.2018.01601 http://scihub22266oqcxt.onion/10.3389/fimmu.2018.01601 C6050389!6050389!30050536     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2018 ; 9 (ä): ä Nephropedia Template TP {{tp|p=30050536|t=2018. New Insights Into the Regulation of ?? T Cells by BTN3A and Other BTN/BTNL in Tumor Immunity |pdf=|usr=}}{{30050536}} gab.com Text New Insights Into the Regulation of T Cells by BTN3A and Other BTN/BTNL in Tumor Immunity JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=30050536 #FOAvip Recent findings in the immunology field have pointed out the emergent role of butyrophilins/butyrophilin-like molecules (BTN/BTNL in human, Btn/Btnl in mouse) in the modulation of ?? T cells. As long as the field develops exponentially, new relationships between certain ?? T cell subsets, on one hand, and their BTN/BTNL counterparts mainly present on epithelial and tumor cells, on the other, are described in the scientific literature. Btnl1/Btnl6 in mice and BTNL3/BTNL8 in humans regulate the homing and maturation of V?7+ and V?4+ T cells to the gut epithelium. Similarly, Skint-1 has shown to shape the dendritic epidermal T cells repertoire and their activation levels in mice. We and others have identified BTN3A proteins are the key mediators of phosphoantigen sensing by human V?9V?2 T cells. Here, we first synthesize the modulation of specific ?? T cell subsets by related BTN/BTNL molecules, in human and mice. Then, we focus on the role of BTN3A in the activation of V?9V?2 T cells, and we highlight the recent advances in the understanding of the expression, regulation, and function of BTN3A in tumor immunity. Hence, recent studies demonstrated that several signals induced by cancer cells or their microenvironment can regulate the expression of BTN3A. Moreover, antibodies targeting BTN3A have shown in vitro and in vivo efficacy in human tumors such as acute myeloid leukemia or pancreatic cancer. We thus finally discuss how these findings could help develop novel ?? T cell-based immunotherapeutical approaches. Twit Text FOAVip New Insights Into the Regulation of T Cells by BTN3A and Other BTN/BTNL in Tumor Immunity ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=30050536 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30050536 #FOAvip English Wikipedia <ref>{{Cite pmid|30050536}}</ref> New Insights Into the Regulation of ?? T Cells by BTN3A and Other BTN/BTNL in Tumor Immunity #MMPMID30050536 Blazquez JL; Benyamine A; Pasero C; Olive D Front Immunol 2018[]; 9 (ä): ä PMID30050536show ga Recent findings in the immunology field have pointed out the emergent role of butyrophilins/butyrophilin-like molecules (BTN/BTNL in human, Btn/Btnl in mouse) in the modulation of ?? T cells. As long as the field develops exponentially, new relationships between certain ?? T cell subsets, on one hand, and their BTN/BTNL counterparts mainly present on epithelial and tumor cells, on the other, are described in the scientific literature. Btnl1/Btnl6 in mice and BTNL3/BTNL8 in humans regulate the homing and maturation of V?7+ and V?4+ T cells to the gut epithelium. Similarly, Skint-1 has shown to shape the dendritic epidermal T cells repertoire and their activation levels in mice. We and others have identified BTN3A proteins are the key mediators of phosphoantigen sensing by human V?9V?2 T cells. Here, we first synthesize the modulation of specific ?? T cell subsets by related BTN/BTNL molecules, in human and mice. Then, we focus on the role of BTN3A in the activation of V?9V?2 T cells, and we highlight the recent advances in the understanding of the expression, regulation, and function of BTN3A in tumor immunity. Hence, recent studies demonstrated that several signals induced by cancer cells or their microenvironment can regulate the expression of BTN3A. Moreover, antibodies targeting BTN3A have shown in vitro and in vivo efficacy in human tumors such as acute myeloid leukemia or pancreatic cancer. We thus finally discuss how these findings could help develop novel ?? T cell-based immunotherapeutical approaches. äNew Insights Into the Regulation of ?? T Cells by BTN3A and Other BTN/(epmc).pdf DeepDyve Pubget Overpricing