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10.1007/s10067-017-3824-1 http://scihub22266oqcxt.onion/10.1007/s10067-017-3824-1 C6050169!6050169!28914380     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Rheumatol 2018 ; 37 (5): 1395-9 Nephropedia Template TP {{tp|p=28914380|t=2018. Secretory sphingomyelinase (S-SMase) activity is elevated in patients with rheumatoid arthritis |pdf=|usr=}}{{28914380}} gab.com Text Secretory sphingomyelinase (S-SMase) activity is elevated in patients with rheumatoid arthritis JO: Clin Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=28914380 #FOAvip Objective: The goals of this study were to determine if secretory sphingomyelinase (S-Smase) activity is elevated in patients with rheumatoid arthritis (RA) compared to control subjects, and to examine the relationships of S-Smase activity with functional status, quality of life and RA disease activity measurements. Methods: We collected data on 33 patients who were diagnosed with RA and 17 non- RA controls who were comparable in terms of age, sex and race. Demographic, clinical data and self-reported measures of fatigue, pain and physical function were obtained directly from patients and controls. RA patients also completed quantitative joint assessment using a 28-joint count and functional status and quality of life assessment using the Modified Health Assessment Questionnaire (mHAQ). Archived serum samples were used to analyze retrospectively serum S-SMase activity in patients and controls. Results: The mean serum S-SMase activity was 1.4-fold higher in patients with RA (RA: 2.8 ± 1.0 nmol/mL/hr vs. Controls: 2.0 ± 0.8 nmol/mL/hr; p=0.014). Spearman?s rho correlations between S-Smase activity and oxidant activity, markers of inflammation and endothelial activation with the exception of P-selectin (rho=0.40, p=0.034), measures of disease activity, functional status and quality of life were not statistically significant in patients with RA. Conclusion: We confirmed S-SMase activity is higher among RA patients compared to controls, as in other acute and chronic inflammatory diseases. Future studies can build on the present findings to understand more fully the biologic role(s) of S-SMase activity in RA. Twit Text FOAVip Secretory sphingomyelinase (S-SMase) activity is elevated in patients with rheumatoid arthritis ????Clin Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=28914380 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28914380 #FOAvip English Wikipedia <ref>{{Cite pmid|28914380}}</ref> Secretory sphingomyelinase (S-SMase) activity is elevated in patients with rheumatoid arthritis #MMPMID28914380 Hanaoka BY; Ormseth MJ; Michael Stein C; Banerjee D; Nikolova-Karakashian M; Crofford LJ Clin Rheumatol 2018[May]; 37 (5): 1395-9 PMID28914380show ga Objective: The goals of this study were to determine if secretory sphingomyelinase (S-Smase) activity is elevated in patients with rheumatoid arthritis (RA) compared to control subjects, and to examine the relationships of S-Smase activity with functional status, quality of life and RA disease activity measurements. Methods: We collected data on 33 patients who were diagnosed with RA and 17 non- RA controls who were comparable in terms of age, sex and race. Demographic, clinical data and self-reported measures of fatigue, pain and physical function were obtained directly from patients and controls. RA patients also completed quantitative joint assessment using a 28-joint count and functional status and quality of life assessment using the Modified Health Assessment Questionnaire (mHAQ). Archived serum samples were used to analyze retrospectively serum S-SMase activity in patients and controls. Results: The mean serum S-SMase activity was 1.4-fold higher in patients with RA (RA: 2.8 ± 1.0 nmol/mL/hr vs. Controls: 2.0 ± 0.8 nmol/mL/hr; p=0.014). Spearman?s rho correlations between S-Smase activity and oxidant activity, markers of inflammation and endothelial activation with the exception of P-selectin (rho=0.40, p=0.034), measures of disease activity, functional status and quality of life were not statistically significant in patients with RA. Conclusion: We confirmed S-SMase activity is higher among RA patients compared to controls, as in other acute and chronic inflammatory diseases. Future studies can build on the present findings to understand more fully the biologic role(s) of S-SMase activity in RA. äSecretory sphingomyelinase (S-SMase) activity is elevated in patients (epmc).pdf DeepDyve Pubget Overpricing