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2018 ; 11
(7
): 1152-1157
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Comparison of 25 MHz and 50 MHz ultrasound biomicroscopy for imaging of the lens
and its related diseases
#MMPMID30046532
Shi MY
; Han X
; Zhang JS
; Yan QC
Int J Ophthalmol
2018[]; 11
(7
): 1152-1157
PMID30046532
show ga
AIM: To compare the results of 25 MHz and 50 MHz ultrasound biomicroscopy (UBM)
regarding the image characteristics of the lens and its related diseases and to
discuss the application value of 25 MHz UBM in ophthalmology. METHODS: A total of
302 patients (455 eyes) were included in this study from November 2014 to May
2015. Patient ages ranged from 5 to 89y (mean±SD: 61.0±17.7y). Different
cross-sectional images of the lens were collected to compare and analyze the
image characteristics and anterior segment parameters using 25 MHz and 50 MHz UBM
in axial and longitudinal scanning modes, respectively. SPSS 19.0 for Windows,
paired t-tests and B&A plot analysis were used for data analysis, and a value of
P<0.05 was considered statistically significant. RESULTS: The 25 MHz UBM images
displayed the lens shape more clearly than 50 MHz UBM images. Particularly for
cataracts, the whole opacity of the lens was shown by 25 MHz UBM, but 50 MHz UBM
only showed part of the lens. The means of the anterior segment parameters
obtained using 25 MHz and 50 MHz UBM were as follows: central corneal thickness:
0.55±0.03 and 0.51±0.04 mm, respectively; central anterior chamber depth:
2.48±0.54 and 2.56±0.56 mm, respectively; and central lens thickness: 4.26±0.62
and 4.15±0.56 mm, respectively. A statistically significant difference was found
between the results obtained with 25 MHz UBM and those obtained with 50 MHz UBM.
The two devices had a good agreement in measuring the anterior segment
parameters. CONCLUSION: The 25 MHz UBM had an obvious advantage in showing the
lens shape. It can provide reliable imaging of the lens and its related diseases
and has a high application value for ophthalmology.