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10.1186/s40880-018-0317-9 http://scihub22266oqcxt.onion/10.1186/s40880-018-0317-9 C6042406!6042406!29996946     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancer+Commun+(Lond) 2018 ; 38 (ä): ä Nephropedia Template TP {{tp|p=29996946|t=2018. When fats commit crimes: fatty acid metabolism, cancer stemness and therapeutic resistance |pdf=|usr=}}{{29996946}} gab.com Text When fats commit crimes: fatty acid metabolism, cancer stemness and therapeutic resistance JO: Cancer Commun (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=29996946 #FOAvip The role of fatty acid metabolism, including both anabolic and catabolic reactions in cancer has gained increasing attention in recent years. Many studies have shown that aberrant expression of the genes involved in fatty acid synthesis or fatty acid oxidation correlate with malignant phenotypes including metastasis, therapeutic resistance and relapse. Such phenotypes are also strongly associated with the presence of a small percentage of unique cells among the total tumor cell population. This distinct group of cells may have the ability to self-renew and propagate or may be able to develop resistance to cancer therapies independent of genetic alterations. Therefore, these cells are referred to as cancer stem cells/tumor-initiating cells/drug-tolerant persisters, which are often refractory to cancer treatment and difficult to target. Moreover, interconversion between cancer cells and cancer stem cells/tumor-initiating cells/drug-tolerant persisters may occur and makes treatment even more challenging. This review highlights recent findings on the relationship between fatty acid metabolism, cancer stemness and therapeutic resistance and prompts discussion about the potential mechanisms by which fatty acid metabolism regulates the fate of cancer cells and therapeutic resistance. Twit Text FOAVip When fats commit crimes: fatty acid metabolism, cancer stemness and therapeutic resistance ????Cancer Commun (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=29996946 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29996946 #FOAvip English Wikipedia <ref>{{Cite pmid|29996946}}</ref> When fats commit crimes: fatty acid metabolism, cancer stemness and therapeutic resistance #MMPMID29996946 Kuo CY; Ann DK Cancer Commun (Lond) 2018[]; 38 (ä): ä PMID29996946show ga The role of fatty acid metabolism, including both anabolic and catabolic reactions in cancer has gained increasing attention in recent years. Many studies have shown that aberrant expression of the genes involved in fatty acid synthesis or fatty acid oxidation correlate with malignant phenotypes including metastasis, therapeutic resistance and relapse. Such phenotypes are also strongly associated with the presence of a small percentage of unique cells among the total tumor cell population. This distinct group of cells may have the ability to self-renew and propagate or may be able to develop resistance to cancer therapies independent of genetic alterations. Therefore, these cells are referred to as cancer stem cells/tumor-initiating cells/drug-tolerant persisters, which are often refractory to cancer treatment and difficult to target. Moreover, interconversion between cancer cells and cancer stem cells/tumor-initiating cells/drug-tolerant persisters may occur and makes treatment even more challenging. This review highlights recent findings on the relationship between fatty acid metabolism, cancer stemness and therapeutic resistance and prompts discussion about the potential mechanisms by which fatty acid metabolism regulates the fate of cancer cells and therapeutic resistance. äWhen fats commit crimes: fatty acid metabolism, cancer stemness and th(epmc).pdf DeepDyve Pubget Overpricing