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2018 ; 12
(1
): 201
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gab.com Text
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Lethal outcome of granulomatous acanthamoebic encephalitis in a man who was human
immunodeficiency virus-positive: a case report
#MMPMID29996943
Geith S
; Walochnik J
; Prantl F
; Sack S
; Eyer F
J Med Case Rep
2018[Jul]; 12
(1
): 201
PMID29996943
show ga
BACKGROUND: Acanthamoeba species can cause disseminating infections in
immunocompromised individuals. CASE PRESENTATION: Here, we report a case of
granulomatous acanthamoebic encephalitis with a lethal outcome in a 54-year-old
German man who was human immunodeficiency virus-positive. The diagnosis was based
on symptoms of progressive neurological deficits, including sensorimotor
paralysis of his right leg and deteriorating alertness. Due to the rapid course
and rather late diagnosis of the infection, effective treatment could not be
applied and he died 12 days after hospital admission. CONCLUSIONS: To the best of
our knowledge, this is the second case of granulomatous acanthamoebic
encephalitis reported within Germany. Our case highlights the importance of early
diagnosis of granulomatous acanthamoebic encephalitis to prevent fatal outcome.
|Acanthamoeba/*isolation & purification
[MESH]
|Central Nervous System Protozoal Infections/complications/diagnostic
imaging/*parasitology
[MESH]