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2018 ; 15
(1
): 36
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English Wikipedia
A pragmatic harm reduction approach to manage a large outbreak of wound botulism
in people who inject drugs, Scotland 2015
#MMPMID29996865
Trayner KMA
; Weir A
; McAuley A
; Godbole G
; Amar C
; Grant K
; Penrice G
; Roy K
Harm Reduct J
2018[Jul]; 15
(1
): 36
PMID29996865
show ga
BACKGROUND: People who inject drugs (PWID) are at an increased risk of wound
botulism, a potentially fatal acute paralytic illness. During the first 6 months
of 2015, a large outbreak of wound botulism was confirmed among PWID in Scotland,
which resulted in the largest outbreak in Europe to date. METHODS: A
multidisciplinary Incident Management Team (IMT) was convened to conduct an
outbreak investigation, which consisted of enhanced surveillance of cases in
order to characterise risk factors and identify potential sources of infection.
RESULTS: Between the 24th of December 2014 and the 30th of May 2015, a total of
40 cases were reported across six regions in Scotland. The majority of the cases
were male, over 30 and residents in Glasgow. All epidemiological evidence
suggested a contaminated batch of heroin or cutting agent as the source of the
outbreak. There are significant challenges associated with managing an outbreak
among PWID, given their vulnerability and complex addiction needs. Thus, a
pragmatic harm reduction approach was adopted which focused on reducing the risk
of infection for those who continued to inject and limited consequences for those
who got infected. CONCLUSIONS: The management of this outbreak highlighted the
importance and need for pragmatic harm reduction interventions which support the
addiction needs of PWID during an outbreak of spore-forming bacteria. Given the
scale of this outbreak, the experimental learning gained during this and similar
outbreaks involving spore-forming bacteria in the UK was collated into national
guidance to improve the management and investigation of future outbreaks among
PWID.
|*Harm Reduction
[MESH]
|Adult
[MESH]
|Analgesics, Opioid/chemistry
[MESH]
|Botulism/epidemiology/*prevention & control
[MESH]
|Disease Outbreaks/*prevention & control/statistics & numerical data
[MESH]
|Drug Contamination
[MESH]
|Female
[MESH]
|Heroin Dependence/*epidemiology
[MESH]
|Heroin/chemistry
[MESH]
|Humans
[MESH]
|Male
[MESH]
|Middle Aged
[MESH]
|Risk Factors
[MESH]
|Risk Management
[MESH]
|Scotland/epidemiology
[MESH]
|Wound Infection/epidemiology/*prevention & control
[MESH]