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10.12688/f1000research.13941.1 http://scihub22266oqcxt.onion/10.12688/f1000research.13941.1 C6039948!6039948!30026918     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       F1000Res 2018 ; 7 (ä): ä Nephropedia Template TP {{tp|p=30026918|t=2018. Recent advances in the management of systemic lupus erythematosus |pdf=|usr=}}{{30026918}} gab.com Text Recent advances in the management of systemic lupus erythematosus JO: F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=30026918 #FOAvip Systemic lupus erythematosus (SLE) is a chronic autoimmune disease presenting highly heterogeneous clinical manifestations and multi-systemic involvement. Patients are susceptible to relapse­ and remission, thus making management challenging. Moreover, a considerable number of side effects may occur with conventional therapies; therefore, there is clearly a need for new therapeutic strategies. Since the pathogenesis of SLE is highly complex, it is far from being fully understood. However, greater understanding of the pathways and of the cellular and molecular mediators involved in SLE is being achieved. Emerging evidence has allowed the development of new biological therapeutic options targeting crucial molecular mediators involved in the pathogenesis of SLE. This literature review analyzes the availability of biological and target-directed treatments, phase II and III trials, and new therapies that are being developed for the treatment of SLE. Twit Text FOAVip Recent advances in the management of systemic lupus erythematosus ????F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=30026918 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30026918 #FOAvip English Wikipedia <ref>{{Cite pmid|30026918}}</ref> Recent advances in the management of systemic lupus erythematosus #MMPMID30026918 Sciascia S; Radin M; Roccatello D; Sanna G; Bertolaccini ML F1000Res 2018[]; 7 (ä): ä PMID30026918show ga Systemic lupus erythematosus (SLE) is a chronic autoimmune disease presenting highly heterogeneous clinical manifestations and multi-systemic involvement. Patients are susceptible to relapse­ and remission, thus making management challenging. Moreover, a considerable number of side effects may occur with conventional therapies; therefore, there is clearly a need for new therapeutic strategies. Since the pathogenesis of SLE is highly complex, it is far from being fully understood. However, greater understanding of the pathways and of the cellular and molecular mediators involved in SLE is being achieved. Emerging evidence has allowed the development of new biological therapeutic options targeting crucial molecular mediators involved in the pathogenesis of SLE. This literature review analyzes the availability of biological and target-directed treatments, phase II and III trials, and new therapies that are being developed for the treatment of SLE. äRecent advances in the management of systemic lupus erythematosus (epmc).pdf DeepDyve Pubget Overpricing