Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1002/ajmg.b.32632 http://scihub22266oqcxt.onion/10.1002/ajmg.b.32632 C6039190!6039190!29659143     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Med+Genet+B+Neuropsychiatr+Genet 2018 ; 177 (4): 434-46 Nephropedia Template TP {{tp|p=29659143|t=2018. RASopathies are associated with a distinct personality profile |pdf=|usr=}}{{29659143}} gab.com Text RASopathies are associated with a distinct personality profile JO: Am J Med Genet B Neuropsychiatr Genet http://www.kidney.de/pget.php?&tw=1&pmid=29659143 #FOAvip Personality is a complex, yet partially heritable, trait. Although some Mendelian diseases like Williams-Beuren syndrome are associated with a particular personality profile, studies have failed to assign the personality features to a single gene or pathway. As a family of monogenic disorders caused by mutations in the Ras/MAPK pathway known to influence social behavior, RASopathies are likely to provide insight into the genetic basis of personality.80 subjects diagnosed with cardiofaciocutaneous syndrome, Costello syndrome, neurofibromatosis type I and Noonan syndrome were assessed using a parent-report BFQ-C (Big-Five Questionnaire for Children) evaluating agreeableness, extraversion, conscientiousness, intellect/openness, and neuroticism, along with 55 unaffected sibling controls. A short questionnaire was added to assess sense of humor. RASopathy subjects and sibling controls were compared for individual components of personality, multidimensional personality profiles, and individual questions using Student tests, analysis of variance, and principal component analysis.RASopathy subjects were given lower scores on average compared to sibling controls in agreeableness, extraversion, conscientiousness, openness and sense of humor, and similar scores in neuroticism. When comparing the multidimensional personality profile between groups, RASopathies showed a distinct profile from unaffected siblings, but no difference in this global profile was found within RASopathies, revealing a common profile for the Ras/MAPK-related disorders. In addition, several syndrome-specific strengths or weaknesses were observed in individual domains. We describe for the first time an association between a single pathway and a specific personality profile, providing a better understanding of the genetics underlying personality, and new tools for tailoring educational and behavioral approaches for individuals with RASopathies. Twit Text FOAVip RASopathies are associated with a distinct personality profile ????Am J Med Genet B Neuropsychiatr Genet http://www.kidney.de/pget.php?&tw=1&pmid=29659143 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29659143 #FOAvip English Wikipedia <ref>{{Cite pmid|29659143}}</ref> RASopathies are associated with a distinct personality profile #MMPMID29659143 Bizaoui V; Gage J; Brar R; Rauen KA; Weiss LA Am J Med Genet B Neuropsychiatr Genet 2018[Jun]; 177 (4): 434-46 PMID29659143show ga Personality is a complex, yet partially heritable, trait. Although some Mendelian diseases like Williams-Beuren syndrome are associated with a particular personality profile, studies have failed to assign the personality features to a single gene or pathway. As a family of monogenic disorders caused by mutations in the Ras/MAPK pathway known to influence social behavior, RASopathies are likely to provide insight into the genetic basis of personality.80 subjects diagnosed with cardiofaciocutaneous syndrome, Costello syndrome, neurofibromatosis type I and Noonan syndrome were assessed using a parent-report BFQ-C (Big-Five Questionnaire for Children) evaluating agreeableness, extraversion, conscientiousness, intellect/openness, and neuroticism, along with 55 unaffected sibling controls. A short questionnaire was added to assess sense of humor. RASopathy subjects and sibling controls were compared for individual components of personality, multidimensional personality profiles, and individual questions using Student tests, analysis of variance, and principal component analysis.RASopathy subjects were given lower scores on average compared to sibling controls in agreeableness, extraversion, conscientiousness, openness and sense of humor, and similar scores in neuroticism. When comparing the multidimensional personality profile between groups, RASopathies showed a distinct profile from unaffected siblings, but no difference in this global profile was found within RASopathies, revealing a common profile for the Ras/MAPK-related disorders. In addition, several syndrome-specific strengths or weaknesses were observed in individual domains. We describe for the first time an association between a single pathway and a specific personality profile, providing a better understanding of the genetics underlying personality, and new tools for tailoring educational and behavioral approaches for individuals with RASopathies. äRASopathies are associated with a distinct personality profile (epmc).pdf DeepDyve Pubget Overpricing