Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 280.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 280.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 280.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 280.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29998142
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Asia+Ocean+J+Nucl+Med+Biol
2018 ; 6
(2
): 97-107
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Brain Single Photon Emission Computed Tomography Scan (SPECT) and functional MRI
in Systemic Lupus Erythematosus Patients with Cognitive Dysfunction: A Systematic
Review
#MMPMID29998142
Sahebari M
; Rezaieyazdi Z
; Khodashahi M
; Abbasi B
; Ayatollahi F
Asia Ocean J Nucl Med Biol
2018[Spr]; 6
(2
): 97-107
PMID29998142
show ga
OBJECTIVES: Systemic lupus erythematosus (SLE) is an autoimmune disease with a
wide range of clinical manifestations. Cognitive dysfunction is one of the
manifestations that could present prior to the emergence of any other
neuropsychiatric involvements in SLE. Cognitive dysfunction is a subtle condition
occurring with a high frequency. However, there is no data on the correlation of
cognitive dysfunction with central nervous system (CNS) imaging findings, in
particular single-photon emission computed tomography scan (SPECT) and functional
MRI. We decided to perform a systematic review of brain SPECT and fMRI in SLE
patients with cognitive dysfunction. METHODS: PubMed, Scopus, and Google Scholar
databases were searched until April 2017 with the following keywords: "SLE OR
systemic lupus erythematous OR lupus" AND "functional MRI OR functional magnetic
resonance imaging OR fMRI OR SPECT or SCAN". A total of 1,767articles were found.
Two rheumatologists reviewed the articles and finally 14 articles were selected
for the final systematic review. RESULTS: The fMRI and SPECT imaging techniques
could provide valuable information regarding the SLE patients with cognitive
dysfunction at the early stages of the disease. CONCLUSION: Brain SPECT scan and
fMRI are used as functional imaging tools in SLE. Both of these diagnostic
modalities are sensitive in reflecting the subtle brain damages in SLE patients
with cognitive dysfunction. Brain fMRI and SPECT scan could be significantly
beneficial in the diagnosis and initial management of cognitive dysfunction in
SLE. Nevertheless, prospective studies could be useful in confirming the
application of these diagnostic modalities in the clinical setting.