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2018 ; 6
(2
): 167-170
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Sagliker Syndrome in a Patient with Secondary Hyperparathyroidism and Chronic
Renal Insufficiency: A Case Report
#MMPMID29998151
Shakeri S
; Zarehparvar Moghadam S
; Sadeghi R
; Ayati N
Asia Ocean J Nucl Med Biol
2018[Spr]; 6
(2
): 167-170
PMID29998151
show ga
Sagliker syndrome is a rare form of renal osteodystrophy resulted from untreated
secondary hyperparathyroidism. It is described by severe skeletal deformities,
high level of PTH in patients with chronic renal failure, and deformed face. This
paper reports a 44-year-old male patient with the mentioned characteristics. In
addition to the unique clinical features, high levels of ALP and PTH hormones
encouraged us to search for syndrome-like a disease, which clinically and
paraclinically matched the Sagliker syndrome. This case highlights the importance
of clinicians' attention for early monitoring and appropriate treatment as it is
shown to be effective in preventing irreversible complications such as soft
tissue and bone abnormalities and cardiovascular impairment in patients with
Sagliker syndrome. Therefore, considering the syndrome is recommended as one of
the diagnostic hypothesis in young patients with renal insufficiency, secondary
hyperparathyroidism, and skeletal deformities.