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2018 ; 20
(4
): 330-335
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Penile sensory thresholds in subtypes of premature ejaculation: implications of
comorbid erectile dysfunction
#MMPMID29405168
Chen X
; Wang FX
; Hu C
; Yang NQ
; Dai JC
Asian J Androl
2018[Jul]; 20
(4
): 330-335
PMID29405168
show ga
Penile hypersensitivity plays an important role in premature ejaculation (PE),
but differences in penile sensitivity among subtypes of PE are unknown.
Therefore, we compared penile sensory thresholds in PE subtypes of lifelong and
acquired PE, PE with and without erectile dysfunction (ED), PE with an
intravaginal ejaculation latency time ?1 min and >1 min, and PE with and without
orgasmic pleasure perceptual dysfunction. During August 2014 to January 2016, 136
patients with PE were included. Penile warm, cold, and vibratory thresholds were
measured. Data of clinical characteristics, sexual life, Premature Ejaculation
Diagnostic Tool (PEDT) score, and the 5-item version of the International Index
of Erectile Function (IIEF-5) score were collected. Vibratory thresholds of the
PE with ED group were higher in the right coronal sulcus (median amplitude: 4.92
vs 3.65 ? m, P = 0.02) and the right penile shaft (median amplitude: 3.87 vs 3.30
? m, P = 0.03), while differences in penile sensory thresholds between other
subtypes were not significant. The median PEDT score was lower in the PE without
ED group (12 vs 14, P < 0.001). The IIEF-5 and PEDT scores were negatively
correlated (r = -0.29, P < 0.001). Patients with orgasmic pleasure perceptual
dysfunction had a lower median IIEF-5 score (20 vs 21, P = 0.02). Patients with
PE and ED had lower penile sensitivity, and ED was associated with more severe
symptoms and weaker orgasmic pleasure perception. In men with PE, management of
comorbid ED is necessary. In case of side effects in erectile function, topical
anesthetics should be cautiously used in men with PE and ED.