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10.1016/j.tibs.2017.08.005

http://scihub22266oqcxt.onion/10.1016/j.tibs.2017.08.005
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C6038137!6038137!28927699
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suck abstract from ncbi


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pmid28927699      Trends+Biochem+Sci 2017 ; 42 (11): 887-98
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  • Biochemical mechanisms of pathogen restriction by intestinal bacteria #MMPMID28927699
  • Rangan KJ; Hang HC
  • Trends Biochem Sci 2017[Nov]; 42 (11): 887-98 PMID28927699show ga
  • The intestine is a highly complex ecosystem where many bacterial species interact with each other and host cells to influence animal physiology and susceptibility to pathogens. Genomic methods have provided a broad framework for understanding how alterations in microbial communities are associated with host physiology and infection, but the biochemical mechanisms of specific intestinal bacterial species are only emerging. In this review, we focus on recent studies that have characterized the biochemical mechanisms by which intestinal bacteria interact with other bacteria and host pathways to restrict pathogen infection. Understanding the biochemical mechanisms of intestinal microbiota function should provide new opportunities for therapeutic development towards a variety of infectious diseases.
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