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10.3892/ol.2018.8947 http://scihub22266oqcxt.onion/10.3892/ol.2018.8947 C6036566!6036566 !30013655     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\30013655 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Oncol+Lett 2018 ; 16 (2 ): 2606-2612 Nephropedia Template TP {{tp|p=30013655 |t=2018. Fusobacterium nucleatum promotes the progression of colorectal cancer by interacting with E-cadherin |pdf=|usr=}}{{30013655 }} gab.com Text Fusobacterium nucleatum promotes the progression of colorectal cancer by interacting with E-cadherin JO: Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=30013655 #FOAvip Increasing evidence suggests that Fusobacterium nucleatum is involved in colorectal carcinogenesis. Previous studies have explored whether F. nucleatum may trigger colonic epithelial-mesenchymal transition. The results of the present study demonstrated that F. nucleatum enhances the proliferation and invasion of NCM460 cells compared with that of normal control and DH5? cells. Furthermore, F. nucleatum significantly increased the phosphorylation of p65 (a subunit of nuclear factor-?B), as well as the expression of interleukin (IL)-6, IL-1? and matrix metalloproteinase (MMP)-13. Additionally, F. nucleatum infection did not affect the expression levels of epithelial (E-)cadherin and ?-catenin. E-cadherin knockdown in NCM460 cells did not induce the activation of inflammatory responses in response to F. nucleatum infection, whereas it increased inflammation in response to ?-catenin silencing. F. nucleatum infection could not increase the proportion of cells at S phase when E-cadherin was silenced. Nevertheless, F. nucleatum infection enhanced the proportion of NCM460 cells at S phase when transfected with small interfering RNAs to knock down ?-catenin expression. In conclusion, the results of the present study demonstrated that F. nucleatum infection interacted with E-cadherin instead of ?-catenin, which in turn enhances the malignant phenotype of colorectal cancer cells. Twit Text FOAVip Fusobacterium nucleatum promotes the progression of colorectal cancer by interacting with E-cadherin ????Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=30013655 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30013655 #FOAvip English Wikipedia <ref>{{Cite pmid|30013655 }}</ref> Fusobacterium nucleatum promotes the progression of colorectal cancer by interacting with E-cadherin #MMPMID30013655 Ma CT ; Luo HS ; Gao F ; Tang QC ; Chen W Oncol Lett 2018[Aug]; 16 (2 ): 2606-2612 PMID30013655 show ga Increasing evidence suggests that Fusobacterium nucleatum is involved in colorectal carcinogenesis. Previous studies have explored whether F. nucleatum may trigger colonic epithelial-mesenchymal transition. The results of the present study demonstrated that F. nucleatum enhances the proliferation and invasion of NCM460 cells compared with that of normal control and DH5? cells. Furthermore, F. nucleatum significantly increased the phosphorylation of p65 (a subunit of nuclear factor-?B), as well as the expression of interleukin (IL)-6, IL-1? and matrix metalloproteinase (MMP)-13. Additionally, F. nucleatum infection did not affect the expression levels of epithelial (E-)cadherin and ?-catenin. E-cadherin knockdown in NCM460 cells did not induce the activation of inflammatory responses in response to F. nucleatum infection, whereas it increased inflammation in response to ?-catenin silencing. F. nucleatum infection could not increase the proportion of cells at S phase when E-cadherin was silenced. Nevertheless, F. nucleatum infection enhanced the proportion of NCM460 cells at S phase when transfected with small interfering RNAs to knock down ?-catenin expression. In conclusion, the results of the present study demonstrated that F. nucleatum infection interacted with E-cadherin instead of ?-catenin, which in turn enhances the malignant phenotype of colorectal cancer cells. äFusobacterium nucleatum promotes the progression of colorectal cancer (epmc).pdf DeepDyve Pubget Overpricing