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10.7150/ijms.25543 http://scihub22266oqcxt.onion/10.7150/ijms.25543 C6036087!6036087!30008592     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Med+Sci 2018 ; 15 (8): 816-22 Nephropedia Template TP {{tp|p=30008592|t=2018. Intestinal dysbiosis activates renal renin-angiotensin system contributing to incipient diabetic nephropathy |pdf=|usr=}}{{30008592}} gab.com Text Intestinal dysbiosis activates renal renin-angiotensin system contributing to incipient diabetic nephropathy JO: Int J Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=30008592 #FOAvip Considerable interest nowadays has focused on gut microbiota owing to their pleiotropic roles in human health and diseases. This intestinal community can arouse a variety of activities in the host and function as ?a microbial organ? by generating bioactive metabolites and participating in a series of metabolism-dependent pathways. Alternations in the composition of gut microbiota, referred to as intestinal dysbiosis, are reportedly associated with several diseases, especially diabetes mellitus and its complications. Here we focus on the relationship between gut microbiota and diabetic nephropathy (DN), as the latter is one of the major causes of chronic kidney diseases. The activation of renin angiotensin system (RAS) is a critical factor to the onset of DN, and emerging data has demonstrated a provoking and mediating role of gut microbiota for this system in the context of metabolic diseases. The purpose of the current review is to highlight some research updates about the underlying interplay between gut microbiota, their metabolites, and the development and progression of DN, along with exploring innovative approaches to targeting this intestinal community as a therapeutic perspective in clinical management of DN patients. Twit Text FOAVip Intestinal dysbiosis activates renal renin-angiotensin system contributing to incipient diabetic nephropathy ????Int J Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=30008592 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30008592 #FOAvip English Wikipedia <ref>{{Cite pmid|30008592}}</ref> Intestinal dysbiosis activates renal renin-angiotensin system contributing to incipient diabetic nephropathy #MMPMID30008592 Lu CC; Ma KL; Ruan XZ; Liu BC Int J Med Sci 2018[]; 15 (8): 816-22 PMID30008592show ga Considerable interest nowadays has focused on gut microbiota owing to their pleiotropic roles in human health and diseases. This intestinal community can arouse a variety of activities in the host and function as ?a microbial organ? by generating bioactive metabolites and participating in a series of metabolism-dependent pathways. Alternations in the composition of gut microbiota, referred to as intestinal dysbiosis, are reportedly associated with several diseases, especially diabetes mellitus and its complications. Here we focus on the relationship between gut microbiota and diabetic nephropathy (DN), as the latter is one of the major causes of chronic kidney diseases. The activation of renin angiotensin system (RAS) is a critical factor to the onset of DN, and emerging data has demonstrated a provoking and mediating role of gut microbiota for this system in the context of metabolic diseases. The purpose of the current review is to highlight some research updates about the underlying interplay between gut microbiota, their metabolites, and the development and progression of DN, along with exploring innovative approaches to targeting this intestinal community as a therapeutic perspective in clinical management of DN patients. äIntestinal dysbiosis activates renal renin-angiotensin system contribu(epmc).pdf DeepDyve Pubget Overpricing