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10.1016/j.jaad.2016.12.005 http://scihub22266oqcxt.onion/10.1016/j.jaad.2016.12.005 C6035868!6035868!28139263     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Am+Acad+Dermatol 2017 ; 76 (4): 736-44 Nephropedia Template TP {{tp|p=28139263|t=2017. JAK inhibitors in dermatology: the promise of a new drug class |pdf=|usr=}}{{28139263}} gab.com Text JAK inhibitors in dermatology: the promise of a new drug class JO: J Am Acad Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=28139263 #FOAvip New molecularly targeted therapeutics are changing dermatologic therapy. JAK-STAT is an intracellular signaling pathway upon which many different pro-inflammatory signaling pathways converge. Numerous inflammatory dermatoses are driven by soluble inflammatory mediators which rely on JAK-STAT signaling, and inhibition of this pathway using JAK inhibitors may be a useful therapeutic strategy for these diseases. There is growing evidence that JAK inhibitors are efficacious in atopic dermatitis, alopecia areata, psoriasis, and vitiligo. Additional evidence suggests that JAK inhibition may be broadly useful in dermatology, with early reports of efficacy in several other conditions. JAK inhibitors can be administered orally or used topically and represent a promising new class of medications. The use of JAK inhibitors in dermatology is reviewed here. Twit Text FOAVip JAK inhibitors in dermatology: the promise of a new drug class ????J Am Acad Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=28139263 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28139263 #FOAvip English Wikipedia <ref>{{Cite pmid|28139263}}</ref> JAK inhibitors in dermatology: the promise of a new drug class #MMPMID28139263 Damsky W; King BA J Am Acad Dermatol 2017[Apr]; 76 (4): 736-44 PMID28139263show ga New molecularly targeted therapeutics are changing dermatologic therapy. JAK-STAT is an intracellular signaling pathway upon which many different pro-inflammatory signaling pathways converge. Numerous inflammatory dermatoses are driven by soluble inflammatory mediators which rely on JAK-STAT signaling, and inhibition of this pathway using JAK inhibitors may be a useful therapeutic strategy for these diseases. There is growing evidence that JAK inhibitors are efficacious in atopic dermatitis, alopecia areata, psoriasis, and vitiligo. Additional evidence suggests that JAK inhibition may be broadly useful in dermatology, with early reports of efficacy in several other conditions. JAK inhibitors can be administered orally or used topically and represent a promising new class of medications. The use of JAK inhibitors in dermatology is reviewed here. äJAK inhibitors in dermatology: the promise of a new drug class (epmc).pdf DeepDyve Pubget Overpricing