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10.1038/s41598-018-28405-x http://scihub22266oqcxt.onion/10.1038/s41598-018-28405-x C6035219!6035219 !29980706     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29980706 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Sci+Rep 2018 ; 8 (1 ): 10262 Nephropedia Template TP {{tp|p=29980706 |t=2018. Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study |pdf=|usr=}}{{29980706 }} gab.com Text Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=29980706 #FOAvip Glucocorticoids (GC) are effective for treating IgG4-related disease (IgG4-RD); however, relapse is often observed. We conducted a retrospective multicentre study to investigate risk factors in GC regimens associated with relapses of IgG4-RD. Data on 166 patients with definitive IgG4-RD diagnosis were collected from 12 institutions. Comprehensive surveillance of clinical backgrounds and GC regimens as well as multivariate analysis of factors associated with treatment responses and relapses was performed. To determine the initial maximal GC dose, the patients were stratified into three groups depending on the initial prednisolone (PSL) dosage: <0.39, 0.4-0.69 and >0.7?mg/kg/day. The multivariate analysis extracted the disease duration and reduction speed of initial GC dose. Patients treated with initial GC <0.39 or >0.7?mg/kg/day of PSL showed higher relapse rates than those treated with 0.4-0.69?mg/kg/day. The relapse rates were significantly higher in patients with fast reduction of the initial dose (>0.4?mg/day) than in patients with slow reduction (<0.4?mg/day). To avoid relapse, 0.4-0.69?mg/kg/day of initial PSL with slow reduction speed (<0.4?mg/day) is needed in the early treatment of IgG4-RD. Twit Text FOAVip Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=29980706 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29980706 #FOAvip English Wikipedia <ref>{{Cite pmid|29980706 }}</ref> Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study #MMPMID29980706 Shirakashi M ; Yoshifuji H ; Kodama Y ; Chiba T ; Yamamoto M ; Takahashi H ; Uchida K ; Okazaki K ; Ito T ; Kawa S ; Yamada K ; Kawano M ; Hirata S ; Tanaka Y ; Moriyama M ; Nakamura S ; Kamisawa T ; Matsui S ; Tsuboi H ; Sumida T ; Shibata M ; Goto H ; Sato Y ; Yoshino T ; Mimori T Sci Rep 2018[Jul]; 8 (1 ): 10262 PMID29980706 show ga Glucocorticoids (GC) are effective for treating IgG4-related disease (IgG4-RD); however, relapse is often observed. We conducted a retrospective multicentre study to investigate risk factors in GC regimens associated with relapses of IgG4-RD. Data on 166 patients with definitive IgG4-RD diagnosis were collected from 12 institutions. Comprehensive surveillance of clinical backgrounds and GC regimens as well as multivariate analysis of factors associated with treatment responses and relapses was performed. To determine the initial maximal GC dose, the patients were stratified into three groups depending on the initial prednisolone (PSL) dosage: <0.39, 0.4-0.69 and >0.7?mg/kg/day. The multivariate analysis extracted the disease duration and reduction speed of initial GC dose. Patients treated with initial GC <0.39 or >0.7?mg/kg/day of PSL showed higher relapse rates than those treated with 0.4-0.69?mg/kg/day. The relapse rates were significantly higher in patients with fast reduction of the initial dose (>0.4?mg/day) than in patients with slow reduction (<0.4?mg/day). To avoid relapse, 0.4-0.69?mg/kg/day of initial PSL with slow reduction speed (<0.4?mg/day) is needed in the early treatment of IgG4-RD. |Adolescent [MESH] |Adult [MESH] |Aged [MESH] |Aged, 80 and over [MESH] |Anti-Inflammatory Agents/*therapeutic use [MESH] |Female [MESH] |Humans [MESH] |Immunoglobulin G4-Related Disease/*drug therapy [MESH] |Male [MESH] |Middle Aged [MESH] |Prednisolone/*therapeutic use [MESH] |Recurrence [MESH] |Retrospective Studies [MESH] |Risk Factors [MESH] |Treatment Outcome [MESH]Factors in glucocorticoid regimens associated with treatment response (epmc).pdf DeepDyve Pubget Overpricing