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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Lancet+Infect+Dis 2018 ; 18 (7): e220-7 Nephropedia Template TP
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The eyes have it: influenza virus infection beyond the respiratory tract #MMPMID29477464
Belser JA; Lash RR; Garg S; Tumpey TM; Maines TR
Lancet Infect Dis 2018[Jul]; 18 (7): e220-7 PMID29477464show ga
Avian and human influenza A viruses alike have shown a capacity to use the eye as a portal of entry and cause ocular disease in human beings. However, whereas influenza viruses generally represent a respiratory pathogen and only occasionally cause ocular complications, the H7 virus subtype stands alone in possessing an ocular tropism. Clarifying what confers such non-respiratory tropism to a respiratory virus will permit a greater ability to identify, treat, and prevent zoonotic human infection following ocular exposure to influenza viruses; especially those within the H7 subtype, which continue to cause avian epidemics on many continents.