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10.1016/j.jacbts.2017.05.004 http://scihub22266oqcxt.onion/10.1016/j.jacbts.2017.05.004 C6034459!6034459!30062153     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       JACC+Basic+Transl+Sci 2017 ; 2 (3): 341-3 Nephropedia Template TP {{tp|p=30062153|t=2017. Nitric Oxide Signaling in Heart Failure With Preserved Ejection Fraction |pdf=|usr=}}{{30062153}} gab.com Text Nitric Oxide Signaling in Heart Failure With Preserved Ejection Fraction JO: JACC Basic Transl Sci http://www.kidney.de/pget.php?&tw=1&pmid=30062153 #FOAvip There has been considerable focus on the potential role of nitric oxide (NO) and phosphodiesterase (PDE)-5 inhibition in treating heart failure with preserved ejection fraction (HFpEF). However, the results from studies have been conflicting. In a preclinical study, pre-treatment of diabetic rats with a PDE-5 inhibitor, vardenafil, resulted in a significant decrease in left ventricle stiffness. However, the results from clinical trials have been neutral. In this perspective piece, the authors discuss whether or not it is time to move on from targeting NO and PDE5 for the treatment of HFpEF. Twit Text FOAVip Nitric Oxide Signaling in Heart Failure With Preserved Ejection Fraction ????JACC Basic Transl Sci http://www.kidney.de/pget.php?&tw=1&pmid=30062153 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30062153 #FOAvip English Wikipedia <ref>{{Cite pmid|30062153}}</ref> Nitric Oxide Signaling in Heart Failure With Preserved Ejection Fraction #MMPMID30062153 Cruz L; Ryan JJ JACC Basic Transl Sci 2017[Jun]; 2 (3): 341-3 PMID30062153show ga There has been considerable focus on the potential role of nitric oxide (NO) and phosphodiesterase (PDE)-5 inhibition in treating heart failure with preserved ejection fraction (HFpEF). However, the results from studies have been conflicting. In a preclinical study, pre-treatment of diabetic rats with a PDE-5 inhibitor, vardenafil, resulted in a significant decrease in left ventricle stiffness. However, the results from clinical trials have been neutral. In this perspective piece, the authors discuss whether or not it is time to move on from targeting NO and PDE5 for the treatment of HFpEF. äNitric Oxide Signaling in Heart Failure With Preserved Ejection Fracti(epmc).pdf DeepDyve Pubget Overpricing