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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Radiol+Case+Rep
2018 ; 13
(4
): 871-877
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Dilated Virchow-Robin space and Parkinson s disease: A case report of combined
MRI and diffusion tensor imaging
#MMPMID29988793
Conforti R
; Sardaro A
; Negro A
; Caiazzo G
; Paccone A
; De Micco R
; Cirillo S
; Tessitore A
Radiol Case Rep
2018[Aug]; 13
(4
): 871-877
PMID29988793
show ga
In this manuscript we report the case of a 69-year-old female patient, who
suffers from Parkinson's disease (PD) with a dilated Virchow-Robin space (dVRS)
on the left anterior perforated substance. During a magnetic resonance imaging
examination, the presence of a dVRS was discovered on the left anterior
perforated substance. Subsequently, the patient has been subjected to further
investigation of magnetic resonance imaging and diffusion tensor imaging (DTI).
The DTI data of our PD patient showed increased peak frequency of left fractional
anisotropy and decreases in the distribution of Mean Diffusivity(MD) with changes
in the fiber density compared to the normal contralateral tract. We hypothesize
that the DTI changes are due to dVRS. In the text a review of the recent
literature on the presence of dVRSs, located in mono and bilateral seat, in
patients with PD is reported, explaining its possible implications on disease
progression, cognitive decline, and worsening of symptoms.