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2018 ; 19
(1
): 160
Nephropedia Template TP
gab.com Text
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English Wikipedia
An atypical presentation of high potassium renal secretion rate in a patient with
thyrotoxic periodic paralysis: a case report
#MMPMID29973184
Tu ML
; Fang YW
; Leu JG
; Tsai MH
BMC Nephrol
2018[Jul]; 19
(1
): 160
PMID29973184
show ga
BACKGROUND: Hypokalemia is one of the most common clinical electrolyte imbalance
problems, and thyrotoxic periodic paralysis (TPP) is a leading cause of
presentation to the emergency department. Low renal potassium secretion rates, a
normal acid-base balance in the blood, and hyperthyroidism are the hallmarks of
suspected TPP. CASE PRESENTATION: Here we report the case of a 36-year-old man
who presented to the emergency department with a sudden onset of acute muscle
weakness at 5 h prior to admission. Biochemistry tests revealed hypokalemia with
hyperthyroidism and renal potassium wasting. TPP was initially not favored due to
the presence of renal potassium wasting. However, his serum potassium level
rebounded rapidly within several hours after potassium supplementation,
indicating that the intracellular shifting of potassium ions was the main
etiology for his hypokalemia. The early stage of TPP development may have
contributed to this paradox. CONCLUSION: Therefore, it is premature to rule out
TPP based on the presentation of high renal potassium secretion rates alone. This
finding may result in an incorrect impression being made in the early stage of
TTP and may consequently lead to an inappropriate potassium supplementation
policy.