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10.1016/j.nicl.2018.05.014

http://scihub22266oqcxt.onion/10.1016/j.nicl.2018.05.014
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C6029563!6029563!29984163
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suck abstract from ncbi


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pmid29984163      Neuroimage+Clin 2018 ; 19 (ä): 551-8
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  • The relationship between brain atrophy and cognitive-behavioural symptoms in retired Canadian football players with multiple concussions #MMPMID29984163
  • Misquitta K; Dadar M; Tarazi A; Hussain MW; Alatwi MK; Ebraheem A; Multani N; Khodadadi M; Goswami R; Wennberg R; Tator C; Green R; Colella B; Davis KD; Mikulis D; Grinberg M; Sato C; Rogaeva E; Louis Collins D; Tartaglia MC
  • Neuroimage Clin 2018[]; 19 (ä): 551-8 PMID29984163show ga
  • Multiple concussions, particularly in contact sports, have been associated with cognitive deficits, psychiatric impairment and neurodegenerative diseases like chronic traumatic encephalopathy. We used volumetric and deformation-based morphometric analyses to test the hypothesis that repeated concussions may be associated with smaller regional brain volumes, poorer cognitive performance and behavioural symptoms among former professional football players compared to healthy controls. This study included fifty-three retired Canadian Football League players, 25 age- and education-matched healthy controls, and controls from the Cambridge Centre for Aging and Neuroscience database for validation. Volumetric analyses revealed greater hippocampal atrophy than expected for age in former athletes with multiple concussions than controls and smaller left hippocampal volume was associated with poorer verbal memory performance in the former athletes. Deformation-based morphometry confirmed smaller bilateral hippocampal volume that was associated with poorer verbal memory performance in athletes. Repeated concussions may lead to greater regional atrophy than expected for age.
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