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10.3390/pharmaceutics10020040 http://scihub22266oqcxt.onion/10.3390/pharmaceutics10020040 C6027251!6027251!29601486     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pharmaceutics 2018 ; 10 (2): ä Nephropedia Template TP {{tp|p=29601486|t=2018. In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases |pdf=|usr=}}{{29601486}} gab.com Text In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases JO: Pharmaceutics http://www.kidney.de/pget.php?&tw=1&pmid=29601486 #FOAvip In situ-based gel drug delivery systems that can bypass the blood-brain barrier, deliver the therapeutics to the desired site, reduce peripheral toxicity and control drug release kinetics have been developed. Some of the therapeutics used to treat neurological diseases suffer from poor bioavailability. Preclinical reports from several researchers have proven that the delivery of drugs to the brain via the nose-to-brain route using in situ gels holds great promise. However, safety issues on the toxicity of the nasal mucosa, transportation of the drugs to specific brain regions and determination of the required dose are factors that must be considered when designing these gels. This review will be focused on in situ-based gels that are used for the delivery of therapeutics via the nose-to-brain route, preclinical reports and challenges. Twit Text FOAVip In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases ????Pharmaceutics http://www.kidney.de/pget.php?&tw=1&pmid=29601486 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29601486 #FOAvip English Wikipedia <ref>{{Cite pmid|29601486}}</ref> In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases #MMPMID29601486 Aderibigbe BA Pharmaceutics 2018[Jun]; 10 (2): ä PMID29601486show ga In situ-based gel drug delivery systems that can bypass the blood-brain barrier, deliver the therapeutics to the desired site, reduce peripheral toxicity and control drug release kinetics have been developed. Some of the therapeutics used to treat neurological diseases suffer from poor bioavailability. Preclinical reports from several researchers have proven that the delivery of drugs to the brain via the nose-to-brain route using in situ gels holds great promise. However, safety issues on the toxicity of the nasal mucosa, transportation of the drugs to specific brain regions and determination of the required dose are factors that must be considered when designing these gels. This review will be focused on in situ-based gels that are used for the delivery of therapeutics via the nose-to-brain route, preclinical reports and challenges. äIn Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neu(epmc).pdf DeepDyve Pubget Overpricing