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10.1186/s12933-018-0738-4 http://scihub22266oqcxt.onion/10.1186/s12933-018-0738-4 C6026339!6026339 !29960584     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29960584 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cardiovasc+Diabetol 2018 ; 17 (1 ): 94 Nephropedia Template TP {{tp|p=29960584 |t=2018. Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy |pdf=|usr=}}{{29960584 }} gab.com Text Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy JO: Cardiovasc Diabetol http://www.kidney.de/pget.php?&tw=1&pmid=29960584 #FOAvip Patients with diabetes type 2 have an increased risk for cardiovascular disease and commonly use combination therapy consisting of the anti-diabetic drug metformin and a cholesterol-lowering statin. However, both drugs act on glucose and lipid metabolism which could lead to adverse effects when used in combination as compared to monotherapy. In this review, the proposed molecular mechanisms of action of statin and metformin therapy in patients with diabetes and dyslipidemia are critically assessed, and a hypothesis for mechanisms underlying interactions between these drugs in combination therapy is developed. Twit Text FOAVip Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy ????Cardiovasc Diabetol http://www.kidney.de/pget.php?&tw=1&pmid=29960584 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29960584 #FOAvip English Wikipedia <ref>{{Cite pmid|29960584 }}</ref> Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy #MMPMID29960584 van Stee MF ; de Graaf AA ; Groen AK Cardiovasc Diabetol 2018[Jun]; 17 (1 ): 94 PMID29960584 show ga Patients with diabetes type 2 have an increased risk for cardiovascular disease and commonly use combination therapy consisting of the anti-diabetic drug metformin and a cholesterol-lowering statin. However, both drugs act on glucose and lipid metabolism which could lead to adverse effects when used in combination as compared to monotherapy. In this review, the proposed molecular mechanisms of action of statin and metformin therapy in patients with diabetes and dyslipidemia are critically assessed, and a hypothesis for mechanisms underlying interactions between these drugs in combination therapy is developed. |Animals [MESH] |Biomarkers/blood [MESH] |Blood Glucose/*drug effects/metabolism [MESH] |Cardiovascular Diseases/blood/diagnosis/epidemiology/*prevention & control [MESH] |Diabetes Mellitus, Type 2/blood/diagnosis/*drug therapy/epidemiology [MESH] |Drug Interactions [MESH] |Dyslipidemias/blood/diagnosis/*drug therapy/epidemiology [MESH] |Humans [MESH] |Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects/pharmacokinetics/*therapeutic use [MESH] |Hypoglycemic Agents/adverse effects/pharmacokinetics/*therapeutic use [MESH] |Lipid Metabolism/drug effects [MESH] |Lipids/*blood [MESH] |Metformin/adverse effects/pharmacokinetics/*therapeutic use [MESH] |Risk Factors [MESH]Actions of metformin and statins on lipid and glucose metabolism and p(epmc).pdf DeepDyve Pubget Overpricing