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Remission of aggressive autoimmune disease (dermatomyositis) with removal of
infective jaw pathology and ozone therapy: review and case report
#MMPMID29959639
Rowen RJ
Auto Immun Highlights
2018[Jun]; 9
(1
): 7
PMID29959639
show ga
INTRODUCTION: This case uniquely reports a connection between endodontically
infected teeth and systemic disease, and additionally presents ozone therapy as a
unique therapy and immune system modulator. It is the world's first such reported
case and the treatment holds invaluable lessons in assessing the "unknown" causes
of autoimmunity and inflammation. Additionally, it presents ozone therapy as a
most needed unique, non-toxic and powerful anti-infective agent,
anti-inflammatory and immune modulator. CASE PRESENTATION: The patient was a
Mexican male field laborer, age 48 years, in inflammatory crisis with a confirmed
case of dermatomyositis. He had received massive prednisone, and powerful immune
suppressing drugs just to function, while disease still raged. I encountered him
in the field in June 2012 with severe muscle pain, weakness, and diffuse
generalized skin rash, essentially unable to do his work. Creatine kinase peaked
at 9293 U/L. History and physical examination findings caused suspicion of
subclinical infections in endodontically treated teeth. This impression was
confirmed in subsequent dental evaluation. He fully recovered after dental
infections were confirmed and surgically removed, while receiving ozone therapy
until all symptoms and laboratory abnormalities normalized. CONCLUSION: Dental
focus of occult infection may be a prime cause/trigger of autoimmune disorders
and inflammatory disorders, requiring surgical intervention to remove. Ozone
therapy, little known in conventional medicine, has been shown in the literature
and in this case to be a powerful and safe immune modulator and anti-infective
agent. This case has significant relevance across the entire spectrum of both
medical and dental practice. It also emphasizes the need for individualized
assessment and treatment rather than symptomatic pharmacological approaches
treating a "disease" rather than the patient. Subclinical dental infection and
ozone therapy are reviewed.