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10.3390/v10060327 http://scihub22266oqcxt.onion/10.3390/v10060327 C6024678!6024678!29914064     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viruses 2018 ; 10 (6): ä Nephropedia Template TP {{tp|p=29914064|t=2018. The Diversity of Bacterial Lifestyles Hampers Bacteriophage Tenacity |pdf=|usr=}}{{29914064}} gab.com Text The Diversity of Bacterial Lifestyles Hampers Bacteriophage Tenacity JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=29914064 #FOAvip Phage therapy is based on a simple concept: the use of a virus (bacteriophage) that is capable of killing specific pathogenic bacteria to treat bacterial infections. Since the pioneering work of Félix d?Herelle, bacteriophages (phages) isolated in vitro have been shown to be of therapeutic value. Over decades of study, a large number of rather complex mechanisms that are used by phages to hijack bacterial resources and to produce their progeny have been deciphered. While these mechanisms have been identified and have been studied under optimal conditions in vitro, much less is known about the requirements for successful viral infections in relevant natural conditions. This is particularly true in the context of phage therapy. Here, we highlight the parameters affecting phage replication in both in vitro and in vivo environments, focusing, in particular, on the mammalian digestive tract. We propose avenues for increasing the knowledge-guided implementation of phages as therapeutic tools. Twit Text FOAVip The Diversity of Bacterial Lifestyles Hampers Bacteriophage Tenacity ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=29914064 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29914064 #FOAvip English Wikipedia <ref>{{Cite pmid|29914064}}</ref> The Diversity of Bacterial Lifestyles Hampers Bacteriophage Tenacity #MMPMID29914064 Lourenço M; De Sordi L; Debarbieux L Viruses 2018[Jun]; 10 (6): ä PMID29914064show ga Phage therapy is based on a simple concept: the use of a virus (bacteriophage) that is capable of killing specific pathogenic bacteria to treat bacterial infections. Since the pioneering work of Félix d?Herelle, bacteriophages (phages) isolated in vitro have been shown to be of therapeutic value. Over decades of study, a large number of rather complex mechanisms that are used by phages to hijack bacterial resources and to produce their progeny have been deciphered. While these mechanisms have been identified and have been studied under optimal conditions in vitro, much less is known about the requirements for successful viral infections in relevant natural conditions. This is particularly true in the context of phage therapy. Here, we highlight the parameters affecting phage replication in both in vitro and in vivo environments, focusing, in particular, on the mammalian digestive tract. We propose avenues for increasing the knowledge-guided implementation of phages as therapeutic tools. äThe Diversity of Bacterial Lifestyles Hampers Bacteriophage Tenacity (epmc).pdf DeepDyve Pubget Overpricing