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10.1186/s40880-018-0314-z

http://scihub22266oqcxt.onion/10.1186/s40880-018-0314-z
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C6020249!6020249!29941042
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suck abstract from ncbi


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pmid29941042      Cancer+Commun+(Lond) 2018 ; 38 (ä): ä
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  • Parkinson?s disease-associated protein Parkin: an unusual player in cancer #MMPMID29941042
  • Liu J; Zhang C; Hu W; Feng Z
  • Cancer Commun (Lond) 2018[]; 38 (ä): ä PMID29941042show ga
  • The mutation of the Parkin gene is a cause of familial Parkinson?s disease. A growing body of evidence suggests that Parkin also functions as a tumor suppressor. Parkin is an ubiquitin E3 ligase, and plays important roles in a variety of cellular processes implicated in tumorigenesis, including cell cycle, cell proliferation, apoptosis, metastasis, mitophagy and metabolic reprogramming. Here we review the role and mechanism of Parkin in cancer.
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