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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Front+Physiol 2018 ; 9 (ä): ä Nephropedia Template TP
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Logical Modeling and Analysis of Cellular Regulatory Networks With GINsim 3 0 #MMPMID29971008
Front Physiol 2018[]; 9 (ä): ä PMID29971008show ga
The logical formalism is well adapted to model large cellular networks, in particular when detailed kinetic data are scarce. This tutorial focuses on this well-established qualitative framework. Relying on GINsim (release 3.0), a software implementing this formalism, we guide the reader step by step toward the definition, the analysis and the simulation of a four-node model of the mammalian p53-Mdm2 network.