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10.1016/j.jpeds.2018.03.030 http://scihub22266oqcxt.onion/10.1016/j.jpeds.2018.03.030 C6016557!6016557 !29752172     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29752172 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Pediatr 2018 ; 198 (ä): 247-253.e1 Nephropedia Template TP {{tp|p=29752172 |t=2018. Social Determinants of Health Are Associated with Markers of Renal Injury in Adolescents with Type 1 Diabetes |pdf=|usr=}}{{29752172 }} gab.com Text Social Determinants of Health Are Associated with Markers of Renal Injury in Adolescents with Type 1 Diabetes JO: J Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=29752172 #FOAvip OBJECTIVE: To examine the relationship between the social determinants of health and markers of early renal injury in adolescent patients with type 1 diabetes (T1D). STUDY DESIGN: Renal outcomes included estimated glomerular filtration rate (eGFR) and albumin-creatinine excretion ratio (ACR). Differences in urinary and serum inflammatory markers also were assessed in relation to social determinants of health. Regression analysis was used to evaluate the association between the Ontario Marginalization Index (ON-Marg) as a measure of the social determinants of health, patient characteristics, ACR, eGFR, and renal filtration status (hyperfiltration vs normofiltration). RESULTS: Participants with T1D (n?=?199) with a mean age of 14.4?±?1.7 years and diabetes duration of 7.2?±?3.1 years were studied. Mean eGFR was 122.0?±?19.4?mL/min/1.73?m(2). Increasing marginalization was positively associated with eGFR (P?<?.0001) but not with ACR (P?=?.605). Greater marginalization was associated with greater median levels of urinary interleukin (IL)-2, IL-12 (p40), macrophage-derived chemokine, monocyte chemoattractant protein-3, and tumor necrosis factor-? and serum IL-2. ON-Marg was significantly associated with eGFR after we controlled for age, sex, body mass index z score, ethnicity, serum glucose, and hemoglobin A1c in linear regression. A similar association between hyperfiltration and ON-Marg score was observed in multivariable logistic regression. CONCLUSION: Increasing marginalization is significantly associated with both eGFR and hyperfiltration in adolescents with T1D and is associated with significant changes in urinary inflammatory biomarkers. These findings highlight a potentially important interaction between social and biological determinants of health in adolescents with T1D. Twit Text FOAVip Social Determinants of Health Are Associated with Markers of Renal Injury in Adolescents with Type 1 Diabetes ????J Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=29752172 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29752172 #FOAvip English Wikipedia <ref>{{Cite pmid|29752172 }}</ref> Social Determinants of Health Are Associated with Markers of Renal Injury in Adolescents with Type 1 Diabetes #MMPMID29752172 Cummings LAM ; Clarke A ; Sochett E ; Daneman D ; Cherney DZ ; Reich HN ; Scholey JW ; Dunger DB ; Mahmud FH J Pediatr 2018[Jul]; 198 (ä): 247-253.e1 PMID29752172 show ga OBJECTIVE: To examine the relationship between the social determinants of health and markers of early renal injury in adolescent patients with type 1 diabetes (T1D). STUDY DESIGN: Renal outcomes included estimated glomerular filtration rate (eGFR) and albumin-creatinine excretion ratio (ACR). Differences in urinary and serum inflammatory markers also were assessed in relation to social determinants of health. Regression analysis was used to evaluate the association between the Ontario Marginalization Index (ON-Marg) as a measure of the social determinants of health, patient characteristics, ACR, eGFR, and renal filtration status (hyperfiltration vs normofiltration). RESULTS: Participants with T1D (n?=?199) with a mean age of 14.4?±?1.7 years and diabetes duration of 7.2?±?3.1 years were studied. Mean eGFR was 122.0?±?19.4?mL/min/1.73?m(2). Increasing marginalization was positively associated with eGFR (P? |*Social Determinants of Health [MESH] |Acute Kidney Injury/diagnosis/*etiology [MESH] |Adolescent [MESH] |Biomarkers/metabolism [MESH] |Creatinine/blood [MESH] |Diabetes Mellitus, Type 1/*complications/*psychology [MESH] |Female [MESH] |Glomerular Filtration Rate [MESH] |Humans [MESH] |Inflammation Mediators/metabolism [MESH] |Logistic Models [MESH] |Male [MESH] |Serum Albumin, Human/metabolism [MESH]Social Determinants of Health Are Associated with Markers of Renal Inj(epmc).pdf DeepDyve Pubget Overpricing